PUM3

PUM3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4WZR, 4WZW
Identifiers
Aliases	PUM3, D19Bwg1357e, 1110069H02Rik, AA675048, Kiaa0020, HA-8, HLA-HA8, PEN, PUF-A, PUF6, XTP5, KIAA0020, pumilio RNA binding family member 3
External IDs	OMIM: 609960; MGI: 106253; HomoloGene: 5762; GeneCards: PUM3; OMA:PUM3 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	2,844,095 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	27,407,225 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; mucosa of transverse colon; ; mucosa of esophagus; ; gonad; ; testicle; ; olfactory zone of nasal mucosa; ; left ovary; ; minor salivary glands; ; body of pancreas; ; right ovary;
	Top expressed in
	Paneth cell; ; renal corpuscle; ; endothelial cell of lymphatic vessel; ; epiblast; ; primitive streak; ; medullary collecting duct; ; internal carotid artery; ; ureter; ; abdominal wall; ; hair follicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; mRNA binding; RNA binding;
Cellular component	endoplasmic reticulum; nucleus; nucleoplasm; nucleolus; chromosome;
Biological process	regulation of protein ADP-ribosylation; regulation of translation;
	Sources:Amigo / QuickGO
Orthologs
	9933
	52874
	ENSG00000080608
	ENSMUSG00000041360
	Q15397
	Q8BKS9
	NM_001031691; NM_014878
	NM_177474
	NP_055693
	NP_803425
	Wikidata
View/Edit Human	View/Edit Mouse

pumilio RNA binding family member 3 (previously KIAA0020^[5]) is a protein that in humans is encoded by the PUM3 gene.^[6]^[7]^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000080608 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041360 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "PUM3 Symbol Report | HUGO Gene Nomenclature Committee". www.genenames.org. Retrieved 2017-01-24.
^ Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (Dec 1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Research. 1 (1): 27–35. doi:10.1093/dnares/1.1.27. PMID 7584026.
^ Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (Dec 1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)". DNA Research. 1 (1): 47–56. doi:10.1093/dnares/1.1.47. PMID 7584028.
^ "Entrez Gene: KIAA0020 KIAA0020".

Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hoja MR, Wahlestedt C, Höög C (August 2000). "A visual intracellular classification strategy for uncharacterized human proteins". Experimental Cell Research. 259 (1): 239–46. doi:10.1006/excr.2000.4948. PMID 10942595.
Brickner AG, Warren EH, Caldwell JA, Akatsuka Y, Golovina TN, Zarling AL, Shabanowitz J, Eisenlohr LC, Hunt DF, Engelhard VH, Riddell SR (January 2001). "The immunogenicity of a new human minor histocompatibility antigen results from differential antigen processing". The Journal of Experimental Medicine. 193 (2): 195–206. doi:10.1084/jem.193.2.195. PMC 2193344. PMID 11148223.
Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (January 2002). "Directed proteomic analysis of the human nucleolus". Current Biology. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Warren EH, Otterud BE, Linterman RW, Brickner AG, Engelhard VH, Leppert MF, Martin PJ, Riddell SR (April 2002). "Feasibility of using genetic linkage analysis to identify the genes encoding T cell-defined minor histocompatibility antigens". Tissue Antigens. 59 (4): 293–303. doi:10.1034/j.1399-0039.2002.590407.x. PMID 12135428.
Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (November 2002). "Functional proteomic analysis of human nucleolus". Molecular Biology of the Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (January 2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000080608 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041360 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] "PUM3 Symbol Report | HUGO Gene Nomenclature Committee". www.genenames.org. Retrieved 2017-01-24.

[pmid7584026-6] Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (Dec 1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Research. 1 (1): 27–35. doi:10.1093/dnares/1.1.27. PMID 7584026.

[pmid7584028-7] Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (Dec 1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)". DNA Research. 1 (1): 47–56. doi:10.1093/dnares/1.1.47. PMID 7584028.

[entrez-8] "Entrez Gene: KIAA0020 KIAA0020".

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References

Further reading