Jedi1

Jedi1
Names
	Preferred IUPAC name 2-methyl-5-phenylfuran-3-carboxylic acid
Identifiers
CAS Number	108124-17-0 ;
3D model (JSmol)	Interactive image;
PubChem CID	736516;
CompTox Dashboard (EPA)	DTXSID30353051 ;
	InChI InChI=1S/C12H10O3/c1-8-10(12(13)14)7-11(15-8)9-5-3-2-4-6-9/h2-7H,1H3,(H,13,14) Key: VLMNACSEESRUAK-UHFFFAOYSA-N;
	SMILES CC1=C(C=C(O1)C2=CC=CC=C2)C(=O)O;
Properties
Chemical formula	C12H10O3
Molar mass	202.209 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Jedi1 (IUPAC name: 2-methyl-5-phenylfuran-3-carboxylic acid) is a chemical compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception.^[1]^[2]

References

^ Wang Y, Chi S, Guo H, Li G, Wang L, Zhao Q, et al. (April 2018). "A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel". Nature Communications. 9 (1): 1300. Bibcode:2018NatCo...9.1300W. doi:10.1038/s41467-018-03570-9. PMC 5880808. PMID 29610524.
^ Fang XZ, Zhou T, Xu JQ, Wang YX, Sun MM, He YJ, Pan SW, Xiong W, Peng ZK, Gao XH, Shang Y (January 2021). "Structure, kinetic properties and biological function of mechanosensitive Piezo channels". Cell & Bioscience. 11 (1): 13. doi:10.1186/s13578-020-00522-z. PMC 7796548. PMID 33422128.

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[1] Wang Y, Chi S, Guo H, Li G, Wang L, Zhao Q, et al. (April 2018). "A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel". Nature Communications. 9 (1): 1300. Bibcode:2018NatCo...9.1300W. doi:10.1038/s41467-018-03570-9. PMC 5880808. PMID 29610524.

[Fang_2021-2] Fang XZ, Zhou T, Xu JQ, Wang YX, Sun MM, He YJ, Pan SW, Xiong W, Peng ZK, Gao XH, Shang Y (January 2021). "Structure, kinetic properties and biological function of mechanosensitive Piezo channels". Cell & Bioscience. 11 (1): 13. doi:10.1186/s13578-020-00522-z. PMC 7796548. PMID 33422128.

[1]

[2]

See also

References