According to Santa Rosa, his decision to name the album Irrepitible was he that "never made a bad disc".[1] The album contains guest stars including Latin pop singer Kany García, Johnny Ventura, and veteran salsa singer Rubén Blades.[2] Originally, the album was stated to be an all-duet album but time constraints had forced Santa Rosa to work with those who is close to him.[2]Irrepetible was announced on May 28, 2010.[3] The first single, "Vivir Sin Ti" (To Live Without You), was released on July 6, 2010, and reached #1 on the Latin Tropical Airplay chart.[4][5] The single did not perform well on the Top Latin Songs peaking at the bottom #50.
Irrepetible became a #1 debut on the Tropical Albums on the week of July 17, 2010.[7] For the Top Latin Albums chart, Irrepetible debuted and peaked on #3.[8]