Inolimomab
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Monoclonal antibody
Monoclonal antibody | |
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Type | Whole antibody |
Source | Mouse |
Target | CD25 |
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Inolimomab is a mouse monoclonal antibody developed as an immunosuppressive drug against graft-versus-host disease. Its target is the alpha chain of the interleukin-2 receptor.[1][2]
References
[edit]- ^ Piñana JL, Valcárcel D, Martino R, Moreno ME, Sureda A, Briones J, et al. (November 2006). "Encouraging results with inolimomab (anti-IL-2 receptor) as treatment for refractory acute graft-versus-host disease". Biology of Blood and Marrow Transplantation. 12 (11): 1135–1141. doi:10.1016/j.bbmt.2006.06.010. PMID 17085306.
- ^ Dartois C, Freyer G, Michallet M, Hénin E, You B, Darlavoix I, et al. (2007). "Exposure-effect population model of inolimomab, a monoclonal antibody administered in first-line treatment for acute graft-versus-host disease". Clinical Pharmacokinetics. 46 (5): 417–432. doi:10.2165/00003088-200746050-00004. PMC 2760126. PMID 17465640.
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Extracellular |
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Unsorted |
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IL-1 |
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IL-2 | |||||
IL-3 | |||||
IL-4 |
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IL-5 |
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IL-6 |
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IL-7 |
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IL-8 |
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IL-9 |
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IL-10 |
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IL-11 |
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IL-12 |
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IL-13 |
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IL-15 |
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IL-17 |
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IL-18 |
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IL-20 |
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IL-21 |
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IL-22 |
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IL-23 |
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IL-27 |
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IL-28 | |||||
IL-31 |
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IL1RL1 |
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IL1RL2 |
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Others |
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This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it. |
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