Influenza non-structural protein
Appearance
Influenza non-structural protein (NS1) | |||||||||||
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Identifiers | |||||||||||
Symbol | Flu_NS1 | ||||||||||
Pfam | PF00600 | ||||||||||
InterPro | IPR000256 | ||||||||||
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Influenza non-structural protein (NS1) is a homodimeric RNA-binding protein found in influenza virus that is required for viral replication. NS1 binds polyA tails of mRNA keeping them in the nucleus. NS1 inhibits pre-mRNA splicing by tightly binding to a specific stem-bulge of U6 snRNA.[1]