From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Heat shock protein beta-2 is a protein that in humans is encoded by the HSPB2 gene .[ 5] [ 6] [ 7]
HSPB2 has been shown to interact with:
^ a b c GRCh38: Ensembl release 89: ENSG00000170276 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038086 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Iwaki A, Nagano T, Nakagawa M, Iwaki T, Fukumaki Y (February 1998). "Identification and characterization of the gene encoding a new member of the alpha-crystallin/small hsp family, closely linked to the alphaB-crystallin gene in a head-to-head manner". Genomics . 45 (2): 386–94. doi :10.1006/geno.1997.4956 . PMID 9344664 . ^ a b Suzuki A, Sugiyama Y, Hayashi Y, Nyu-i N, Yoshida M, Nonaka I, Ishiura S, Arahata K, Ohno S (April 1998). "MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase" . J Cell Biol . 140 (5): 1113–24. doi :10.1083/jcb.140.5.1113 . PMC 2132705 PMID 9490724 . ^ "Entrez Gene: HSPB2 heat shock 27kDa protein 2" .^ a b Sugiyama Y, Suzuki A, Kishikawa M, Akutsu R, Hirose T, Waye MM, Tsui SK, Yoshida S, Ohno S (January 2000). "Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation" . J. Biol. Chem . 275 (2): 1095–104. doi :10.1074/jbc.275.2.1095 PMID 10625651 . ^ Sun X, Fontaine JM, Rest JS, Shelden EA, Welsh MJ, Benndorf R (January 2004). "Interaction of human HSP22 (HSPB8) with other small heat shock proteins" . J. Biol. Chem . 279 (4): 2394–402. doi :10.1074/jbc.M311324200 PMID 14594798 . ^ Benndorf R, Sun X, Gilmont RR, Biederman KJ, Molloy MP, Goodmurphy CW, Cheng H, Andrews PC, Welsh MJ (July 2001). "HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27)" . J. Biol. Chem . 276 (29): 26753–61. doi :10.1074/jbc.M103001200 PMID 11342557 . ^ Wu Y, Liu J, Zhang Z, Huang H, Shen J, Zhang S, Jiang Y, Luo L, Yin Z (January 2009). "HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination". Cell. Signal . 21 (1): 143–50. doi :10.1016/j.cellsig.2008.10.001 . PMID 18950704 .
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