From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
17β-Hydroxysteroid dehydrogenase type 14 also known as 17β-HSD type 14 or 17βHSD14 is an enzyme that in humans is encoded by the HSD17B14 gene .[ 5] [ 6]
17βHSD14 catalyzes the stereospecific oxidation and reduction of the 17β carbon atom of androgens and estrogens using NAD(P)(H) as a cofactor. It is primarily expressed in glandular epithelial tissues of breast, ovary, and testis.[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000087076 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030825 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Zhu YS, Imperato-McGinley JL (9 November 2016). "4.02: Disorders of Sexual Development in Males: Molecular Genetics, Epigenetics, Gender Identity, and Cognition" . In Lightman S (ed.). Hormones, Brain and Behavior . Vol. 4: Clinical Important Effects of Hormones on Brain and Behavior. Elsevier Science. p. 69. ISBN 978-0-12-803608-2 ^ Zanders ED (9 November 2015). Human Drug Targets: A Compendium for Pharmaceutical Discovery ISBN 978-1-118-84985-9 ^ Sivik T, Vikingsson S, Gréen H, Jansson A (2012). "Expression patterns of 17β-hydroxysteroid dehydrogenase 14 in human tissues" . Hormone and Metabolic Research . 44 (13): 949–56. doi :10.1055/s-0032-1321815 . PMID 22864907 . S2CID 557122 .
