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HPMPA

From Wikipedia, the free encyclopedia
HPMPA
Names
Preferred IUPAC name
({[(2S)-1-(6-Amino-9H-purin-9-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C9H14N5O5P/c10-8-7-9(12-3-11-8)14(4-13-7)1-6(2-15)19-5-20(16,17)18/h3-4,6,15H,1-2,5H2,(H2,10,11,12)(H2,16,17,18)/t6-/m0/s1
    Key: FRPXSOOHWNMLPH-LURJTMIESA-N
  • c1nc(c2c(n1)n(cn2)C[C@@H](CO)OCP(=O)(O)O)N
Properties
C9H14N5O5P
Molar mass 303.215 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

HPMPA is an experimental broad spectrum antiviral.[1]

References

[edit]
  1. ^ Clercq, Erik De; Holý, Antonin; Rosenberg, Ivan; Sakuma, Takashi; Balzarini, Jan; Maudgal, Parbhat C. (1986). "A novel selective broad-spectrum anti-DNA virus agent". Nature. 323 (6087): 464–467. Bibcode:1986Natur.323..464C. doi:10.1038/323464a0. PMID 3762696. S2CID 19194763.