Gymnascella dankaliensis
| Gymnascella dankaliensis | |
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| Species: | Gymnascella dankaliensis
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Gymnascella dankaliensis is a moderate to slow growing fungus commonly found in the soil of warmer climates.[1][2] It is characterized by round yellow, orange or red-brown ascospores encircled by undifferentiated filaments.[1] They have been found in ear, nail and skin infections.[2] Their metabolites have been isolated and shown to have cytotoxic and anti-tumor properties .[3][4]
Morphology
[edit]Colonies vary greatly in colour, texture and growth rate. Colonies first appear white, then turn a pale yellow or olive and as they mature become yellow-brown to orange brown.[5] The texture can be either cottony, fine, knotted or wispy.[2] Growth rate of colonies varies from moderately slow to rapid.[2][5]
Gymnascella dankaliensis has irregular, indistinct filaments.
Ecology
[edit]Gymnascella dankaliensis has been reported in the soil of climates and the marine sponge Halichondria japonica.[2][6]
Metabolites
[edit]Since the late 1990s, multiple cytotoxic compounds have been isolated from Gymnascella dankaliensis such as:
References
[edit]- ^ a b Atlas of clinical fungi. Hoog, G. S. de. (2nd ed.). Utrecht: Centraalbureau voor Schimmelcultures. 2000. ISBN 978-9070351434. OCLC 46669547.
{{cite book}}: CS1 maint: others (link) - ^ a b c d e Laboratory handbook of dermatophytes : a clinical guide and laboratory handbook of dermatophytes and other filamentous fungi from skin, hair, and nails. Kane, Julius, 1924-. Belmont, CA: Star Pub. 1997. ISBN 978-0898631579. OCLC 37116438.
{{cite book}}: CS1 maint: others (link) - ^ Amagata, Taro; Minoura, Katsuhiko; Numata, Atsushi (October 2006). "Gymnastatins F−H, Cytostatic Metabolites from the Sponge-Derived FungusGymnascella dankaliensis". Journal of Natural Products. 69 (10): 1384–1388. doi:10.1021/np0600189. ISSN 0163-3864. PMID 17067147.
- ^ AMAGATA, TARO; USAMI, YOSHIHIDE; MINOURA, KATSUHIKO; ITO, TADAYOSHI; NUMATA, ATSUSHI (1998). "Cytotoxic Substances Produced by a Fungal Strain from a Sponge: Physico-chemical Properties and Structures". The Journal of Antibiotics. 51 (1): 33–40. doi:10.7164/antibiotics.51.33. ISSN 0021-8820. PMID 9531985.
- ^ a b Pathogenic fungi in humans and animals. Howard, Dexter H., 1927- (2nd ed.). New York: Marcel Dekker. 2003. ISBN 978-0824706838. OCLC 51258022.
{{cite book}}: CS1 maint: others (link) - ^ Li, Min; Zhou, Peijie; Wu, Anmei (May 2006). "Synthesis of Gymnasterone B, an antitumor steroid from Gymnascella dankaliensis". Tetrahedron Letters. 47 (20): 3409–3412. doi:10.1016/j.tetlet.2006.03.072. ISSN 0040-4039.
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