Goblet cell carcinoid
Appearance
Goblet cell carcinoid | |
---|---|
Other names | Crypt cell carcinoma, neuroendocrine tumour with goblet cell differentiation |
Micrograph showing a goblet cell carcinoid. H&E stain. |
The goblet cell carcinoid (GCC) is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma, histologically arising from Paneth cells.[1]
Sign and symptoms
[edit]GCCs may present as appendicitis.
Diagnosis
[edit]GCCs are diagnosed by pathology. They have a characteristic biphasic appearance which includes (1) goblet cell-like cells, and (2) neuroendocrine-type nuclear chromatin (stippled chromatin).
Prognosis
[edit]GCCs have an aggressive course compared to other appendiceal neuroendocrine tumours.[1]
Treatment
[edit]GCCs are treated with surgery.
See also
[edit]References
[edit]External links
[edit]Wikimedia Commons has media related to Goblet cell carcinoid.