Gluconate dehydratase
Appearance
gluconate dehydratase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.1.39 | ||||||||
CAS no. | 37290-75-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme gluconate dehydratase (EC 4.2.1.39) catalyzes the chemical reaction
- D-gluconate 2-dehydro-3-deoxy-D-gluconate + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming). Other names in common use include D-gluconate dehydratase, and D-gluconate hydro-lyase. This enzyme participates in the pentose phosphate pathway.
Structural studies
[edit]As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1QJ4.
References
[edit]- Andreesen JR, Gottschalk G (1969). "The occurrence of a modified Entner-doudoroff pathway in Clostridium aceticum". Arch. Mikrobiol. 69 (2): 160–70. Bibcode:1969ArMic..69..160A. doi:10.1007/BF00409760. PMID 5383859. S2CID 19210429.