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Gentisate decarboxylase

From Wikipedia, the free encyclopedia
gentisate decarboxylase
Identifiers
EC no.4.1.1.62
CAS no.37290-54-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

The enzyme gentisate decarboxylase (EC 4.1.1.62) catalyzes the chemical reaction

2,5-dihydroxybenzoate hydroquinone + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming). Other names in common use include 2,5-dihydroxybenzoate decarboxylase, and gentisate carboxy-lyase. This enzyme participates in tyrosine metabolism.

References

[edit]
  • Grant DJ, Patel JC (1969). "The non-oxidative decarboxylation of p-hydroxybenzoic acid, gentisic acid, protocatechuic acid and gallic acid by Klebsiella aerogenes (Aerobacter aerogenes)". Antonie van Leeuwenhoek. 35 (3): 325–43. doi:10.1007/BF02219153. PMID 5309907.