Galactitol-1-phosphate 5-dehydrogenase
| galactitol-1-phosphate 5-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.251 | ||||||||
| CAS no. | 167618-25-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a galactitol-1-phosphate 5-dehydrogenase (EC 1.1.1.251) is an enzyme that catalyzes the chemical reaction
- galactitol-1-phosphate + NAD+ L-tagatose 6-phosphate + NADH + H+
Thus, the two substrates of this enzyme are galactitol-1-phosphate and NAD+, whereas its 3 products are L-tagatose 6-phosphate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is galactitol-1-phosphate:NAD+ oxidoreductase. This enzyme participates in galactose metabolism. It employs one cofactor, zinc.
References
[edit]- Nobelmann B, Lengeler JW (1995). "Sequence of the gat operon for galactitol utilization from a wild-type strain EC3132 of Escherichia coli". Biochim. Biophys. Acta. 1262 (1): 69–72. doi:10.1016/0167-4781(95)00053-j. PMID 7772602.
