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Protein-coding gene in the species Homo sapiens
HASPIN Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2VUW , 2WB8 , 3DLZ , 3E7V , 3F2N , 3FMD , 3IQ7 , 4OUC , 4QTC , 5HTC , 5HTB
Identifiers Aliases HASPIN , GSG2, germ cell associated 2, haspin, histone H3 associated protein kinaseExternal IDs OMIM : 609240 ; MGI : 1194498 ; HomoloGene : 49236 ; GeneCards : HASPIN ; OMA :HASPIN - orthologs Wikidata
Serine/threonine-protein kinase haspin is an enzyme that in humans is encoded by the GSG2 gene .[ 5]
Dai J, Sullivan BA, Higgins JM (2007). "Regulation of mitotic chromosome cohesion by Haspin and Aurora B." Dev. Cell . 11 (5): 741–50. doi :10.1016/j.devcel.2006.09.018 . PMID 17084365 .
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Dai J, Sultan S, Taylor SS, Higgins JM (2005). "The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment" . Genes Dev . 19 (4): 472–88. doi :10.1101/gad.1267105 . PMC 548948 . PMID 15681610 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 . PMID 14702039 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Higgins JM (2001). "The Haspin gene: location in an intron of the integrin alphaE gene, associated transcription of an integrin alphaE-derived RNA and expression in diploid as well as haploid cells". Gene . 267 (1): 55–69. doi :10.1016/S0378-1119(01)00387-0 . PMID 11311556 .
Tanaka H, Iguchi N, Nakamura Y, et al. (2001). "Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase" . Mol. Hum. Reprod . 7 (3): 211–8. doi :10.1093/molehr/7.3.211 . PMID 11228240 .