GALNT13

GALNT13
Identifiers
Aliases	GALNT13, GalNAc-T13, polypeptide N-acetylgalactosaminyltransferase 13
External IDs	OMIM: 608369; MGI: 2139447; HomoloGene: 62167; GeneCards: GALNT13; OMA:GALNT13 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q23.3-q24.1 Start 153,871,922 bp End 154,453,979 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 C1.1 Start 54,436,317 bp End 55,118,309 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar cortex cerebellar hemisphere right hemisphere of cerebellum gonad corpus callosum testicle C1 segment Achilles tendon secondary oocyte cerebellar vermis Top expressed in lobe of cerebellum habenula cerebellar vermis dorsal striatum lumbar spinal ganglion olfactory tubercle lateral septal nucleus nucleus accumbens substantia nigra neural layer of retina More reference expression data BioGPS n/a
Gene ontology Molecular function glycosyltransferase activity transferase activity metal ion binding carbohydrate binding polypeptide N-acetylgalactosaminyltransferase activity Cellular component integral component of membrane Golgi membrane Golgi apparatus membrane Biological process protein glycosylation O-glycan processing protein O-linked glycosylation protein O-linked glycosylation via serine protein O-linked glycosylation via threonine Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 114805 271786 Ensembl ENSG00000144278 ENSMUSG00000060988 UniProt Q8IUC8 Q8CF93 RefSeq (mRNA) NM_001301627 NM_052917 NM_173030 RefSeq (protein) NP_001288556 NP_443149 NP_001363321 NP_001363323 NP_001363327 NP_001363329 NP_001363330 NP_001363331 NP_001363332 NP_001363333 NP_001363334 NP_766618 Location (UCSC) Chr 2: 153.87 – 154.45 Mb Chr 2: 54.44 – 55.12 Mb PubMed search
Wikidata
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Polypeptide N-acetylgalactosaminyltransferase 13 is an enzyme that in humans is encoded by the GALNT13 gene.

The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM]

Further reading

• Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013. S2CID 25064683.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.