Formimidoylglutamate deiminase
| formimidoylglutamate deiminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.3.13 | ||||||||
| CAS no. | 9054-85-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a formimidoylglutamate deiminase (EC 3.5.3.13) is an enzyme that catalyzes the chemical reaction
- N-formimidoyl-L-glutamate + H2O N-formyl-L-glutamate + NH3
Thus, the two substrates of this enzyme are N-formimidoyl-L-glutamate and H2O, whereas its two products are N-formyl-L-glutamate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is N-formimidoyl-L-glutamate iminohydrolase. Other names in common use include formiminoglutamate deiminase, and formiminoglutamic iminohydrolase. This enzyme participates in histidine metabolism.
References
[edit]- Wickner RB, Tabor H (1971). N-Formimino-L-glutamate iminohydrolase (Pseudomonas sp.). Methods Enzymol. Vol. 17B. pp. 80–84. doi:10.1016/0076-6879(71)17012-7.
