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FlpD RNA motif

From Wikipedia, the free encyclopedia
flpD RNS motif
Consensus secondary structure of flpD RNAs
Identifiers
SymbolflpD RNA
RfamRF01737
Other data
RNA typeCis-regulatory element
Domain(s)Archaea
PDB structuresPDBe

The flpD RNA motif is a conserved RNA structure discovered using bioinformatics.[1] It is detected only in methanogenic archaea, and is generally located in the apparent 5' untranslated region of genes encoding hydrogenases that are likely involved in methane metabolism. For example, the flpD gene itself encodes a subunit of methyl-viologen-reducing hydrogenase.[2]

References

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  1. ^ Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605.
  2. ^ Nölling J, Pihl TD, Vriesema A, Reeve JN (May 1995). "Organization and growth phase-dependent transcription of methane genes in two regions of the Methanobacterium thermoautotrophicum genome". J. Bacteriol. 177 (9): 2460–2468. doi:10.1128/jb.177.9.2460-2468.1995. PMC 176905. PMID 7730278.
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