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File:Neuron with mHtt inclusion.jpg

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Neuron_with_mHtt_inclusion.jpg (362 × 470 pixels, file size: 60 KB, MIME type: image/jpeg)

Description
English: A montage of three images of single striatal neurons transfected with a disease-associated version of huntingtin, the protein that causes Huntington's disease. Nuclei of untransfected neurons are seen in the background (blue). The neuron in the center (yellow) contains an abnormal intracellular accumulation of huntingtin called an inclusion body (orange). Studies using an automated microscope and survival analysis demonstrated that neurons with disease-associated huntingtin that form inclusion bodies survive longer than those that do not, from press release [1], Attribution 'Dr. Steven Finkbeiner, Gladstone Institute of Neurological Disease, The Taube-Koret Center for Huntington's Disease Research, and the University of California San Francisco'
Date
Source Study Using Robotic Microscope Shows How Mutant Huntington's Disease Protein Affects Neurons. Press releases. National Institute of Neurological Disorders and Stroke (2004-10-13). Retrieved on 2009-03-15.
Author Dr. Steven Finkbeiner, Gladstone Institute of Neurological Disease, The Taube-Koret Center for Huntington's Disease Research, and the University of California San Francisco
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Other versions Derivative works of this file:  Neuron with mHTT inclusion zoomed.jpg
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inception

13 October 2004

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Date/TimeThumbnailDimensionsUserComment
current23:39, 14 March 2009Thumbnail for version as of 23:39, 14 March 2009362 × 470 (60 KB)Leevanjackson{{Information |Description={{en|1=single striatal neurons (yellow) transfected with nuclear inclusion (orange) mHtt, other neurons in background (blue), from press release http://www.ninds.nih.gov/news_and_events/press_releases/pressrelease_huntington%27s

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