File:Mitochondrial OMM and matrix in DRP1-KO cells after PXA.png
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Summary
| Description |
English: Fluorescent microscopy image of the mitochondria of a HeLa cell in which the gene DRP1 has been knocked out. The cell had been treated with the mycotoxin phomoxanthone A (PXA) for 30 min. The mitochondrial structure has been severely distorted, resulting in retraction of the outer mitochondrial membrane (stained via TOMM20 and shown in red) and fragmentation of the mitochondrial matrix (stained via HSP60 and shown in green). |
| Date | |
| Source | Böhler et al. (2018) |
| Author | Böhler P, Stuhldreier F, Anand R, Kondadi AK, Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Wu W, Frank M, Niemann H, Wesbuer E, Barbian A, Luyten T, Parys JB, Weidtkamp-Peters S, Borchardt A, Reichert AS, Peña-Blanco A, García-Sáez AJ, Itskanov S, van der Bliek AM, Proksch P, Wesselborg S, Stork B. (2018). "The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane". Cell Death & Disease 9 (3): e286. DOI:10.1038/s41419-018-0312-8. |
| Permission (Reusing this file) |
  This file is licensed under the Creative Commons Attribution 4.0 International license.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 17:14, 20 February 2018 | | 296 × 296 (88 KB) | Shinryuu | == {{int:filedesc}} == {{Information |Description={{en|{{w|Fluorescent microscopy}} image of the {{w|mitochondria}} of a {{w|Mouse embryonic fibroblast|MEF}} cell in which the gene ''{{w|DRP1}}'' has been {{w|Gene knockout|knocked out}}. The cell had been treated with the mycotoxin {{w|phomoxanthone A}} (PXA) for 30 min. The mitochondrial structure has been severely distorted, resulting in retraction of the {{w|outer mitochondrial membrane}} (stained via {{w|TOMM20}} and shown in red) and fragmentation of the {{w|mitochondrial matrix}} (stained via {{w|HSP60}} and shown in green).}} |Source=[https://www.nature.com/articles/s41419-018-0312-8 Böhler et al. (2018)] |Date={{Date|2018|02|19}} |Author={{cite journal | authors = Böhler P, Stuhldreier F, Anand R, Kondadi AK, Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Wu W, Frank M, Niemann H, Wesbuer E, Barbian A, Luyten T, Parys JB, Weidtkamp-Peters S, Borchardt A, Reichert AS, Peña-Blanco A, García-Sáez AJ, Itskanov S, van de... |
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