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File:CuracinA Cyclopropyl Moiety Biosynthesis.pdf

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English: Curacin A has a unique cyclopropyl ring in its structure synthesized by the combination of an HMG-CoA Synthase casette (mevalonate pathway) along with a heme independent halogenase and a unique enoyl reductase that cyclizes the molecule into a cyclopropyl ring. The image shows the biosynthetic steps and enzymes responsible for the cyclopropyl ring formation.
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Author Scienceshaman

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10 June 2015

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