Fe3+-transporting ATPase
| ferric-transporting ATPase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 7.2.2.7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a Fe3+-transporting ATPase (EC 7.2.2.7) is an enzyme that catalyzes the chemical reaction
- ATP + H2O + Fe3+out ADP + phosphate + Fe3+in
The 3 substrates of this enzyme are ATP, H2O, and Fe3+, whereas its 3 products are ADP, phosphate, and Fe3+.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (ferric-ion-transporting). This enzyme participates in abc transporters - general.
References
[edit]- Angerer A, Klupp B, Braun V (1992). "Iron transport systems of Serratia marcescens". J. Bacteriol. 174 (4): 1378–87. PMC 206435. PMID 1531225.
- Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. doi:10.1016/0923-2508(96)81050-3. PMID 7569321.
- Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. PMID 9889977.
- Khun HH, Kirby SD, Lee BC (1998). "A Neisseria meningitidis fbpABC mutant is incapable of using nonheme iron for growth". Infect. Immun. 66 (5): 2330–6. PMC 108199. PMID 9573125.
