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FKBP10

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FKBP10
Identifiers
AliasesFKBP10, FKBP65, OI11, OI6, PPIASE, hFKBP65, BRKS1, FK506 binding protein 10, FKBP prolyl isomerase 10
External IDsOMIM: 607063; MGI: 104769; HomoloGene: 7718; GeneCards: FKBP10; OMA:FKBP10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021939

NM_001163481
NM_010221

RefSeq (protein)

NP_068758

NP_001156953
NP_034351

Location (UCSC)Chr 17: 41.81 – 41.82 MbChr 11: 100.31 – 100.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

FK506-binding protein 10 is a protein that in humans is encoded by the FKBP10 gene.[5][6][7]

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase family. It is located in endoplasmic reticulum and acts as molecular chaperones. Two alternatively spliced variants, which encode different isoform, are reported.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000141756Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001555Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Patterson CE, Schaub T, Coleman EJ, Davis EC (Feb 2001). "Developmental Regulation of FKBP65: An ER-localized Extracellular Matrix Binding-Protein". Mol Biol Cell. 11 (11): 3925–35. doi:10.1091/mbc.11.11.3925. PMC 15047. PMID 11071917.
  6. ^ Ishikawa Y, Vranka J, Wirz J, Nagata K, Bachinger HP (Nov 2008). "The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens". J Biol Chem. 283 (46): 31584–90. doi:10.1074/jbc.M802535200. PMID 18786928.
  7. ^ a b "Entrez Gene: FKBP10 FK506 binding protein 10, 65 kDa".

Further reading

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