FCF1

FCF1
Identifiers
Aliases	FCF1, Bka, C14orf111, UTP24, CGI-35, FCF1 rRNA-processing protein, rRNA-processing protein
External IDs	MGI: 1920986; HomoloGene: 5706; GeneCards: FCF1; OMA:FCF1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	74,738,620 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	85,030,077 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; rectum; ; monocyte; ; amniotic fluid; ; islet of Langerhans; ; mucosa of paranasal sinus; ; gingival epithelium; ; stromal cell of endometrium; ; Achilles tendon; ; palpebral conjunctiva;
	Top expressed in
	primary oocyte; ; yolk sac; ; morula; ; epiblast; ; embryo; ; embryo; ; secondary oocyte; ; blastocyst; ; genital tubercle; ; tail of embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA binding;
Cellular component	small-subunit processome; nucleolus; nucleus; nucleoplasm;
Biological process	ribosome biogenesis; rRNA processing; endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);
	Sources:Amigo / QuickGO
Orthologs
	51077
	73736
	ENSG00000119616
	ENSMUSG00000021243
	Q9Y324
	Q9CTH6
	NM_015962; NM_001318508
	NM_028632
	NP_001305437; NP_057046
	NP_082908
	Wikidata
View/Edit Human	View/Edit Mouse

rRNA-processing protein FCF1 homolog is a protein that in humans is encoded by the FCF1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119616 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021243 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Rempola B, Karkusiewicz I, Piekarska I, Rytka J (Jun 2006). "Fcf1p and Fcf2p are novel nucleolar Saccharomyces cerevisiae proteins involved in pre-rRNA processing". Biochem Biophys Res Commun. 346 (2): 546–54. doi:10.1016/j.bbrc.2006.05.140. PMID 16762320.
^ "Entrez Gene: FCF1 FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)".

Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Wellenreuther R, Schupp I, Poustka A, et al. (2004). "SMART amplification combined with cDNA size fractionation in order to obtain large full-length clones". BMC Genomics. 5 (1): 36. doi:10.1186/1471-2164-5-36. PMC 436056. PMID 15198809.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. Bibcode:2003Natur.421..601H. doi:10.1038/nature01348. PMID 12508121.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.

This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000119616 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021243 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16762320-5] Rempola B, Karkusiewicz I, Piekarska I, Rytka J (Jun 2006). "Fcf1p and Fcf2p are novel nucleolar Saccharomyces cerevisiae proteins involved in pre-rRNA processing". Biochem Biophys Res Commun. 346 (2): 546–54. doi:10.1016/j.bbrc.2006.05.140. PMID 16762320.

[entrez-6] "Entrez Gene: FCF1 FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)".

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References

Further reading