Emavusertib

Emavusertib

Identifiers
IUPAC name N-[5-[(3R)-3-hydroxypyrrolidin-1-yl]-2-morpholin-4-yl-[1,3]oxazolo[4,5-b]pyridin-6-yl]-2-(2-methylpyridin-4-yl)-1,3-oxazole-4-carboxamide
CAS Number	1801344-14-8
PubChem CID	118224491
DrugBank	DB18060
ChemSpider	84492187
UNII	MH5DMF9JKY
ChEMBL	ChEMBL4783351
Chemical and physical data
Formula	C24H25N7O5
Molar mass	491.508 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=NC=CC(=C1)C2=NC(=CO2)C(=O)NC3=CC4=C(N=C3N5CC[C@H](C5)O)N=C(O4)N6CCOCC6
InChI InChI=1S/C24H25N7O5/c1-14-10-15(2-4-25-14)23-27-18(13-35-23)22(33)26-17-11-19-20(28-21(17)31-5-3-16(32)12-31)29-24(36-19)30-6-8-34-9-7-30/h2,4,10-11,13,16,32H,3,5-9,12H2,1H3,(H,26,33)/t16-/m1/s1 Key:SJHNWSAWWOAWJH-MRXNPFEDSA-N

Emavusertib (CA-4948) is a drug which acts as a selective inhibitor of the enzyme Interleukin-1 receptor-associated kinase 4 (IRAK-4) and was developed for the treatment of some forms of cancer.

See also

• Zimlovisertib