From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Epsin-2 is a protein that in humans is encoded by the EPN2 gene .[ 5] [ 6]
This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis . Alternate splicing of this gene results in two transcript variants encoding different isoforms .[ 6]
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