Draft:List of modes of action of insecticides

This is a list of modes of action of insecticides. The common name for the active ingredient which is formulated into the branded product sold to end-users is given, in a table showing the classifications used by the industry-sponsored Insecticide Resistance Action Committee (IRAC), which advises on the use of insecticides in crop protection and classifies the available compounds according to their chemical structures and mechanism of action so as to manage the risks of pesticide resistance developing. The 2024 IRAC poster of insecticide modes of action includes many of chemicals listed below. For a comprehensive list of chemical compounds that have been registered as insecticides, see list of insecticides.

IRAC code	Mode of action	Class	Common name
1	Acetylcholinesterase inhibitors	Carbamate	Pirimicarb
1	Acetylcholinesterase inhibitors	Organophosphate	Pirimiphos-methyl
2	GABA-gated chloride channel blockers	Cyclodiene	Dieldrin
3	Sodium channel modulators	Organochlorine	DDT
3	Sodium channel modulators	Pyrethrin	Cinerin I
3	Sodium channel modulators	Pyrethroid	Cyhalothrin
4	Nicotinic acetylcholine receptor modulators	Neonicotinoid	Imidacloprid
4	Nicotinic acetylcholine receptor modulators	Neonicotinoid	Thiamethoxam
5	Nicotinic acetylcholine receptor allosteric site I	Spinosyns	Spinosad
6	Glutamate-gated chloride channel allosteric modulators	Avermectins	Ivermectin
6	Glutamate-gated chloride channel allosteric modulators	Milbemycins	Milbemycin oxime
7	Juvenile hormone receptor modulators	Juvenile hormone analogs	Methoprene
8	Miscellaneous non-specific inhibitors	Alkyl halides	Ethylene dibromide
8	Miscellaneous non-specific inhibitors	Alkyl halides	Methyl bromide
8	Miscellaneous non-specific inhibitors	Alkyl halides	Methylene chloride
8	Miscellaneous non-specific inhibitors	Chloropicrin	Chloropicrin