Draft:Claus C. Hilgetag (neuroscientist)
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Claus C. Hilgetag (neuroscientist)
[edit]Claus-Christian Hilgetag (also known as Claus Hilgetag or Claus C. Hilgetag) (born in 1969) is a German neuroscientist focusing on theoretical biophysics and network neuroscience. His interests cover the principal organization of brain connectivity.[1][2] [3][4][5][6], the interaction between structure and function in large-scale brain networks[7][8][9], causal brain mapping[10], and simple excitable models of brain dynamics[11].
Life and Career
[edit]Claus Hilgetag obtained a master's degree (Diplom) in Biophysics at Humboldt University, Berlin in 1994, where his research focused on metabolic networks and contributed to the definition of elementary flux modes[12]. His research was supervised by Stefan Schuster. He started his PhD in Computational Neuroscience at the University of Oxford and obtained his degree at Newcastle University (1994-1999). During his PhD, he focused on mathematical approaches to brain connectivity analysis. Although he focused on the hierarchical organization of the visual system in cats and macaques[2], he contributed to works on linking behavioral function to neuronal elements. He was a postdoctoral fellow in the group of Helen Barbas at Boston University at the Department of Anatomy and Neurobiology from 1999 until 2001 as a Wellcome Trust International Fellow. During his fellowship there, he continued his work on brain connectivity and its organization, focusing on laminar patterning and the role of cytoarchitectonic types in brain network architecture. He also worked on modeling paradoxical lesion effects as a consequence of interhemispheric competition among regions of the visual system[13]
In 2001, he moved back to Germany and established his group at Jacobs University of Bremen. During his early years as an assistant and later associate professor, he showed interest in generative network models of nervous systems and contributed to the development of a game-theoretical framework for lesion-symptom mapping. Moreover, he continued his research on the relationship between neuroanatomic and topological features of brain networks[1]. In 2011, he was appointed W3 professor (full professor) at the University Medical Center Hamburg Eppendorf, where he currently directs the Institute of Computational Neuroscience in the Center for Experimental Medicine. He is also an adjunct associate professor at Boston University. In 2015, he was elected as a member of the Academy of Sciences and Humanities in Hamburg.
Besides his scientific works, his contributions to the community include serving as senior editor of Network Neuroscience, PLOS Biology, and Philosophical Transactions of the Royal Society B. He has been awarded several grants by the German Research Foundation (DFG) [14]and participated as principal investigator in several Collaborative Research Centers.
References
[edit]- ^ a b SPORNS, O; CHIALVO, D; KAISER, M; HILGETAG, C (2004). "Organization, development and function of complex brain networks". Trends in Cognitive Sciences. 8 (9): 418–425. doi:10.1016/j.tics.2004.07.008. ISSN 1364-6613. PMID 15350243.
- ^ a b Scannell, J.W. (1999-04-01). "The Connectional Organization of the Cortico-thalamic System of the Cat". Cerebral Cortex. 9 (3): 277–299. doi:10.1093/cercor/9.3.277. ISSN 1460-2199. PMID 10355908.
- ^ CC Hilgetag, GAPC Burns, MA O'Neill, JW Scannell, MP Young, Anatomical connectivity defines the organization of clusters of cortical areas in the macaque and the cat, Philosophical Transactions of the Royal Society of London. Series B
- ^ Zhou, Changsong; Zemanová, Lucia; Zamora, Gorka; Hilgetag, Claus C.; Kurths, Jürgen (2006-12-08). "Hierarchical Organization Unveiled by Functional Connectivity in Complex Brain Networks". Physical Review Letters. 97 (23): 238103. Bibcode:2006PhRvL..97w8103Z. doi:10.1103/physrevlett.97.238103. ISSN 0031-9007. PMID 17280251.
- ^ Neher, Peter F.; Côté, Marc-Alexandre; Houde, Jean-Christophe; Descoteaux, Maxime; Maier-Hein, Klaus H. (2017-01-30). "Fiber tractography using machine learning". NeuroImage. 158: 417–429. doi:10.1101/104190. PMID 28716716. Retrieved 2024-08-01.
- ^ Kaiser, Marcus; Hilgetag, Claus C (2006-07-21). "Nonoptimal Component Placement, but Short Processing Paths, due to Long-Distance Projections in Neural Systems". PLOS Computational Biology. 2 (7): e95. arXiv:q-bio/0607034. Bibcode:2006PLSCB...2...95K. doi:10.1371/journal.pcbi.0020095. ISSN 1553-7358. PMC 1513269. PMID 16848638.
- ^ Ghashghaei, H.T.; Hilgetag, C.C.; Barbas, H. (2007). "Sequence of information processing for emotions based on the anatomic dialogue between prefrontal cortex and amygdala". NeuroImage. 34 (3): 905–923. doi:10.1016/j.neuroimage.2006.09.046. ISSN 1053-8119. PMC 2045074. PMID 17126037.
- ^ Hilgetag, Claus C.; Théoret, Hugo; Pascual-Leone, Alvaro (2001-08-20). "Enhanced visual spatial attention ipsilateral to rTMS-induced 'virtual lesions' of human parietal cortex". Nature Neuroscience. 4 (9): 953–957. doi:10.1038/nn0901-953. ISSN 1097-6256. PMID 11528429.
- ^ Engel, Andreas K.; Gerloff, Christian; Hilgetag, Claus C.; Nolte, Guido (2013). "Intrinsic Coupling Modes: Multiscale Interactions in Ongoing Brain Activity". Neuron. 80 (4): 867–886. doi:10.1016/j.neuron.2013.09.038. PMID 24267648.
- ^ Toba, Monica N.; Zavaglia, Melissa; Malherbe, Caroline; Moreau, Tristan; Rastelli, Federica; Kaglik, Anna; Valabrègue, Romain; Pradat-Diehl, Pascale; Hilgetag, Claus C.; Valero-Cabré, Antoni (2020-04-03). "Game theoretical mapping of white matter contributions to visuospatial attention in stroke patients with hemineglect". Human Brain Mapping. 41 (11): 2926–2950. doi:10.1002/hbm.24987. ISSN 1065-9471. PMC 7336155. PMID 32243676.
- ^ Messé, Arnaud; Hütt, Marc-Thorsten; König, Peter; Hilgetag, Claus C. (2015-01-19). "A closer look at the apparent correlation of structural and functional connectivity in excitable neural networks". Scientific Reports. 5 (1): 7870. Bibcode:2015NatSR...5E7870M. doi:10.1038/srep07870. ISSN 2045-2322. PMC 4297952. PMID 25598302.
- ^ SCHUSTER, STEFAN; HILGETAG, CLAUS (1994). "On Elementary Flux Modes in Biochemical Reaction Systems at Steady State". Journal of Biological Systems. 02 (2): 165–182. doi:10.1142/s0218339094000131. ISSN 0218-3390.
- ^ Hilgetag, Claus C.; Théoret, Hugo; Pascual-Leone, Alvaro (2001-08-20). "Enhanced visual spatial attention ipsilateral to rTMS-induced 'virtual lesions' of human parietal cortex". Nature Neuroscience. 4 (9): 953–957. doi:10.1038/nn0901-953. ISSN 1097-6256. PMID 11528429.
- ^ "DFG - GEPRIS - Professor Dr. Claus Hilgetag". gepris.dfg.de. Retrieved 2024-08-01.