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Draft:Cinfenine

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Cinfenine
Identifiers
  • (E)-N-(2-benzhydryloxyethyl)-N-methyl-3-phenylprop-2-en-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC25H27NO
Molar mass357.497 g·mol−1
3D model (JSmol)
  • CN(CCOC(C1=CC=CC=C1)C2=CC=CC=C2)C/C=C/C3=CC=CC=C3
  • InChI=1S/C25H27NO/c1-26(19-11-14-22-12-5-2-6-13-22)20-21-27-25(23-15-7-3-8-16-23)24-17-9-4-10-18-24/h2-18,25H,19-21H2,1H3/b14-11+
  • Key:QTKQVDXGCWKEHE-SDNWHVSQSA-N

Cinfenine (INNTooltip International Nonproprietary Name) is a drug described as an antidepressant and coronary vasodilator which was never marketed.[1][2][3] It was first described in the literature by 1970.[1][4] The drug is similar in chemical structure to the modafinil derivative and atypical dopamine reuptake inhibitor JJC8-016 as well as to the antihistamine and anticholinergic diphenhydramine and derivatives of diphenhydramine like ebastine.[1][5]

See also

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References

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  1. ^ a b c Elks, J. (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 278. ISBN 978-1-4757-2085-3. Retrieved 20 October 2024.
  2. ^ https://iris.who.int/bitstream/handle/10665/379226/9789240099388-eng.pdf
  3. ^ "CINFENINE". Inxight Drugs. Retrieved 20 October 2024.
  4. ^ "Diphenylmethoxyaethylaminoderivate und Verfahren zu ihrer Herstellung". Google Patents. 22 January 1970. Retrieved 20 October 2024.
  5. ^ "Cinfenine". PubChem. Retrieved 20 October 2024.