Old Post Office, 300 East Main Street, 30°00′15″N 91°49′00″W / 30.00411°N 91.81656°W / 30.00411; -91.81656 (Old Post Office ) , built c.1903. Also listed in East Main Street Historic District .
Pascal Building , 223 East Main Street, 30°00′17″N 91°48′59″W / 30.00459°N 91.81647°W / 30.00459; -91.81647 (Pascal Building ) , built 1889. Also individually listed.
Leblanc & Broussard Ford Dealership, 221 East Main Street, 30°00′17″N 91°49′00″W / 30.00466°N 91.81656°W / 30.00466; -91.81656 (Leblanc & Broussard Ford Dealership ) , built c.1912.
Leblanc & Broussard Service Department Warehouse, 221½ East Main Street, 30°00′18″N 91°48′59″W / 30.00496°N 91.81634°W / 30.00496; -91.81634 (Leblanc & Broussard Service Department Warehouse ) , built 1931.
Davis Building, 133 East Main Street, 30°00′18″N 91°49′02″W / 30.00508°N 91.81728°W / 30.00508; -91.81728 (Davis Building ) , built 1892.
Bayou Teche Museum, 131 East Main Street, 30°00′19″N 91°49′02″W / 30.0052°N 91.81727°W / 30.0052; -91.81727 (Bayou Teche Museum ) , built 1929-30.
Evangeline Theater , 129 East Main Street, 30°00′19″N 91°49′02″W / 30.00528°N 91.81736°W / 30.00528; -91.81736 (Evangeline Theater ) , built 1929-30. Also individually listed.
Crystal Image, 115 East Main Street, 30°00′19″N 91°49′02″W / 30.00528°N 91.81736°W / 30.00528; -91.81736 (Crystal Image ) .
Crystal Image, 115 East Main Street, 30°00′20″N 91°49′04″W / 30.00561°N 91.81773°W / 30.00561; -91.81773 (Crystal Image ) .
Provost's Café, 113 East Main Street, 30°00′20″N 91°49′04″W / 30.00567°N 91.81779°W / 30.00567; -91.81779 (Provost's Café ) . Also known as Armand's and Clementine's Fine Dining.
Building at 111 East Main Street, 30°00′21″N 91°49′04″W / 30.00573°N 91.81784°W / 30.00573; -91.81784 (111 East Main Street ) .
Building at 109 East Main Street, 30°00′21″N 91°49′05″W / 30.00576°N 91.81792°W / 30.00576; -91.81792 (109 East Main Street ) .
Coleman Building, 105 East Main Street, 30°00′21″N 91°49′05″W / 30.00587°N 91.81803°W / 30.00587; -91.81803 (Coleman Building ) .
DeRouen Financial, 103 East Main Street, 30°00′22″N 91°49′05″W / 30.00598°N 91.81799°W / 30.00598; -91.81799 (DeRouen Financial ) .
Renoudet Building, 101 East Main Street, 30°00′22″N 91°49′05″W / 30.00604°N 91.81803°W / 30.00604; -91.81803 (Renoudet Building ) .
Building at 144 West Main Street, 30°00′25″N 91°49′09″W / 30.00705°N 91.81912°W / 30.00705; -91.81912 (144 West Main Street ) . Built 1941.
Building at 144A West Main Street, 30°00′26″N 91°49′08″W / 30.00717°N 91.81895°W / 30.00717; -91.81895 (144A West Main Street ) . Built 1941.
McMahon Furniture Company, 150 West Main Street, 30°00′26″N 91°49′09″W / 30.00727°N 91.81927°W / 30.00727; -91.81927 (McMahon Furniture Company ) . Built 1890.
Satterfield Building, 152 West Main Street, 30°00′26″N 91°49′10″W / 30.00734°N 91.81934°W / 30.00734; -91.81934 (Satterfield Building ) . Built 1881.
Chevron (Gulf) Service Station, 200 West Main Street, 30°00′27″N 91°49′10″W / 30.0076°N 91.81957°W / 30.0076; -91.81957 (Chevron (Gulf) Service Station ) . Built 1927.
Riviere's Jewelry Store, 214 West Main Street, 30°00′28″N 91°49′11″W / 30.00764°N 91.81969°W / 30.00764; -91.81969 (Riviere's Jewelry Store ) . Built 1940s.
Slim's News Stand, 216 West Main Street, 30°00′28″N 91°49′11″W / 30.00768°N 91.81972°W / 30.00768; -91.81972 (Slim's News Stand ) . Built 1940s.
Iberia Steam Laundry, 220 West Main Street, 30°00′28″N 91°49′11″W / 30.00777°N 91.81978°W / 30.00777; -91.81978 (Iberia Steam Laundry ) .
Steinberg Building, 232 West Main Street, 30°00′29″N 91°49′12″W / 30.00812°N 91.8201°W / 30.00812; -91.8201 (Steinberg Building ) . Built c.1880.
American Department Store, 254 West Main Street, 30°00′31″N 91°49′14″W / 30.00858°N 91.82046°W / 30.00858; -91.82046 (American Department Store ) . Built 1950s.
Hebert's Hotel, 213-225 West Main Street, 30°00′28″N 91°49′13″W / 30.00767°N 91.82024°W / 30.00767; -91.82024 (Hebert's Hotel ) .
John R. Taylor Drugstore , 145 West Main Street, 30°00′25″N 91°49′11″W / 30.00695°N 91.81959°W / 30.00695; -91.81959 (John R. Taylor Drugstore ) . Built 1907. Also individually listed.
Bayou Art Gallery, 143 West Main Street, 30°00′25″N 91°49′10″W / 30.00682°N 91.81941°W / 30.00682; -91.81941 (Bayou Art Gallery ) . Built 1870s.
Armentor's Jewelry Store, 137 West Main Street, 30°00′24″N 91°49′10″W / 30.00671°N 91.81934°W / 30.00671; -91.81934 (Armentor's Jewelry Store ) .
Abdalla's Department Store, 131 West Main Street, 30°00′23″N 91°49′10″W / 30.00652°N 91.81941°W / 30.00652; -91.81941 (Abdalla's Department Store ) . Built 1950s-1960s.
Napoleon's on the Teche, 127 West Main Street, 30°00′23″N 91°49′10″W / 30.00644°N 91.81931°W / 30.00644; -91.81931 (Napoleon's on the Teche ) . Built 1950s-1960s.
Abdalla's Department Store Building #3, 131A West Main Street, 30°00′23″N 91°49′09″W / 30.00638°N 91.81923°W / 30.00638; -91.81923 (Abdalla's Department Store Building #3 ) . Built 1950s-1960s.
People's National Bank , 119 West Main Street, 30°00′23″N 91°49′08″W / 30.00631°N 91.81897°W / 30.00631; -91.81897 (People's National Bank ) . Built 1911. Also individually listed.
Building at 109 West Main Street, 30°00′22″N 91°49′08″W / 30.00609°N 91.81884°W / 30.00609; -91.81884 (109 West Main Street ) .
Model Company, 107 West Main Street, 30°00′22″N 91°49′08″W / 30.00603°N 91.81876°W / 30.00603; -91.81876 (Model Company ) .
Building at 105 West Main Street, 30°00′21″N 91°49′07″W / 30.00597°N 91.81871°W / 30.00597; -91.81871 (105 West Main Street ) .
Gougenheim Building, 101 West Main Street, 30°00′21″N 91°49′07″W / 30.00588°N 91.81866°W / 30.00588; -91.81866 (Gougenheim Building ) . Built c.1893. Also known as Hugonin Building and Morgan & Lindsay.
Bowab's, 102 East Main Street, 30°00′21″N 91°49′06″W / 30.00571°N 91.81846°W / 30.00571; -91.81846 (Bowab's ) . Built c.1893.
Creims, 104 East Main Street, 30°00′20″N 91°49′06″W / 30.00566°N 91.8184°W / 30.00566; -91.8184 (Creims ) . Built c.1893.
Babineaux's Shoes, 108 East Main Street, 30°00′20″N 91°49′06″W / 30.00554°N 91.81832°W / 30.00554; -91.81832 (Babineaux's Shoes ) .
Ackal's Department Store, 110 East Main Street, 30°00′20″N 91°49′06″W / 30.00548°N 91.81827°W / 30.00548; -91.81827 (Ackal's Department Store ) .
Wormser's Department Store , 112-116 East Main Street, 30°00′19″N 91°49′05″W / 30.00534°N 91.81816°W / 30.00534; -91.81816 (Wormser's Department Store ) . Built 1932. Also individually listed.
Building at 120 East Main Street, 30°00′19″N 91°49′05″W / 30.00517°N 91.81803°W / 30.00517; -91.81803 (120 East Main Street ) . Built 1950s.
Building at 122 East Main Street, 30°00′18″N 91°49′05″W / 30.00512°N 91.81797°W / 30.00512; -91.81797 (122 East Main Street ) . Built 1950s.
Bazus Building, 210 East Main Street, 30°00′16″N 91°49′02″W / 30.00454°N 91.8172°W / 30.00454; -91.8172 (Bazus Building ) .