Dihydrobenzophenanthridine oxidase
| Dihydrobenzophenanthridine oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.5.3.12 | ||||||||
| CAS no. | 114051-83-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Dihydrobenzophenanthridine oxidase (DHBP oxidase) is an enzyme. In the IUBMB Enzyme Nomenclature, dihydrobenzophenanthridine oxidase is EC 1.5.3.12.
Dihydrobenzophenanthridine oxidase produces oxidized forms of benzophenanthridine alkaloids:
- In Sanguinaria canadensis (bloodroot), dihydrobenzophenanthridine oxidase produces sanguinarine from dihydrosanguinarine, and chelirubine from dihydrochelirubine.
- In Eschscholzia californica (California poppy), dihydrobenzophenanthridine oxidase produces macarpine from dihydromacarpine.
External links
[edit]- Chelirubine, Macarpine and Sanguinarine Biosynthesis
- Ignatov A, Clark WG, Cline SD, Psenak M, Krueger J, Coscia CJ (1996). "Elicitation of dihydrobenzophenanthridine oxidase in Sanguinaria canadensis cell cultures". Phytochemistry. 43 (6): 1141–4. doi:10.1016/S0031-9422(96)00540-7. PMID 8987906.
- Park SU, Yu M, Facchini PJ (2002). "Antisense RNA-mediated suppression of benzophenanthridine alkaloid biosynthesis in transgenic cell cultures of California poppy". Plant Physiol. 128 (2): 696–706. doi:10.1104/pp.010741. PMC 148930. PMID 11842172.
- Rho D, Chauret N, Laberge N, Archambault J (1992). "Growth characteristics of Sanguinaria canadensis L. cell suspensions and immobilized cultures for production of benzophenanthridine alkaloids". Appl. Microbiol. Biotechnol. 36 (5): 611–7. doi:10.1007/BF00183237. PMID 1368065.
- KEGG (Kyoto Encyclopedia of Genes and Genomes) Alkaloid biosynthesis I - Reference pathway
