Diadenosine hexaphosphate hydrolase (ATP-forming)
| Diadenosine hexaphosphate hydrolase (ATP-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.6.1.61 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Diadenosine hexaphosphate hydrolase (ATP-forming) (EC 3.6.1.61, Ndx1) is an enzyme with systematic name P1,P6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (ATP-forming).[1] This enzyme catalyses the following chemical reaction
- (1) P1,P6-bis(5'-adenosyl)hexaphosphate + H2O 2 ATP
- (2) P1,P5-bis(5'-adenosyl)pentaphosphate + H2O ATP + ADP
- (3) P1,P4-bis(5'-adenosyl)tetraphosphate + H2O ATP + AMP
The enzyme requires the presence of the divalent cations (Mn2+, Mg2+, Zn2+, and Co2+).
References
[edit]- ^ Iwai T, Kuramitsu S, Masui R (May 2004). "The Nudix hydrolase Ndx1 from Thermus thermophilus HB8 is a diadenosine hexaphosphate hydrolase with a novel activity". The Journal of Biological Chemistry. 279 (21): 21732–9. doi:10.1074/jbc.m312018200. PMID 15024014.
External links
[edit]- Diadenosine+hexaphosphate+hydrolase+(ATP-forming) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
