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Deacetylisoipecoside synthase

From Wikipedia, the free encyclopedia
deacetylisoipecoside synthase
Identifiers
EC no.4.3.3.3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

The enzyme deacetylisoipecoside synthase (EC 4.3.3.3) catalyzes the chemical reaction

deacetylisoipecoside + H2O dopamine + secologanin

This enzyme belongs to the family of lyases, specifically amine lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is deacetylisoipecoside dopamine-lyase (secologanin-forming). It is also called deacetylisoipecoside dopamine-lyase. It participates in indole and ipecac alkaloid biosynthesis.

References

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  • De-Eknamkul W, Ounaroon A, Tanahashi T, Kutchan TM, Zenk MH (1997). "Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii". Phytochemistry. 45 (3): 477–484. doi:10.1016/S0031-9422(96)00828-X.