DIP2B

DIP2B
Identifiers
Aliases	DIP2B, disco interacting protein 2 homolog B
External IDs	OMIM: 611379; MGI: 2145977; HomoloGene: 72227; GeneCards: DIP2B; OMA:DIP2B - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	50,748,657 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	100,117,354 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; cerebellar vermis; ; subthalamic nucleus; ; corpus callosum; ; medulla oblongata; ; superior vestibular nucleus; ; skin of arm; ; pars reticulata; ; pons; ; external globus pallidus;
	Top expressed in
	vestibular membrane of cochlear duct; ; primary oocyte; ; secondary oocyte; ; blood; ; perirhinal cortex; ; sciatic nerve; ; conjunctival fornix; ; spermatid; ; entorhinal cortex; ; cingulate gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	catalytic activity; molecular function;
Cellular component	cytoplasm; extracellular exosome; membrane; nucleus;
Biological process	metabolism; biological process;
	Sources:Amigo / QuickGO
Orthologs
	57609
	239667
	ENSG00000066084
	ENSMUSG00000023026
	Q9P265
	Q3UH60
	NM_020849; NM_173602
	NM_001159361; NM_172819
	NP_775873
	NP_001152833; NP_766407; NP_001389830
	Wikidata
View/Edit Human	View/Edit Mouse

DIP2 disco-interacting protein 2 homolog B (Drosophila) is a protein that in humans is encoded by the DIP2B gene.^[5] A member of the disco-interacting protein homolog 2 protein family, it contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1, as well as AMP-binding sites. The presence of these sites suggests that DIP2B may participate in DNA methylation. This gene is located near a folate-sensitive fragile site.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000066084 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023026 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "DIP2 disco-interacting protein 2 homolog B (Drosophila)". Retrieved 2011-12-05.
^ Winnepenninckx B, Debacker K, Ramsay J, Smeets D, Smits A, FitzPatrick DR, et al. (February 2007). "CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1". American Journal of Human Genetics. 80 (2): 221–231. doi:10.1086/510800. PMC 1785358. PMID 17236128.

References

Further reading