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Cytidylate cyclase

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cytidylate cyclase
Identifiers
EC no.4.6.1.6
CAS no.65357-82-6
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IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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The enzyme cytidylate cyclase (EC 4.6.1.6) is an enzyme that catalyzes the reaction

CTP = 3′,5′-cyclic CMP + diphosphate

This enzyme belongs to the family of lyases, specifically the class of phosphorus-oxygen lyases. The systematic name of this enzyme class is CTP diphosphate-lyase (cyclizing; 3′,5′-cyclic-CMP-forming). Other names in common use include 3',5'-cyclic-CMP synthase, cytidylyl cyclase, cytidyl cyclase, and CTP diphosphate-lyase (cyclizing).

References

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  • Cech SY, Ignarro LJ (1978). "Cytidine 3',5'-monophosphate (cyclic CMP) formation by homogenates of mouse liver". Biochem. Biophys. Res. Commun. 80 (1): 119–25. doi:10.1016/0006-291X(78)91112-9. PMID 23778.
  • Newton RP, Salih SG, Hakeem NA, Kingston EE, Beynon JH (1985). "3',5'-Cyclic UMP, -cyclic IMP, -cyclic TMP and related enzymes in mammalian-tissues". Biochem. Soc. Trans. 13: 1134–1135.