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Coriell Institute for Medical Research

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Coordinates: 39°56′26″N 75°06′53″W / 39.94059°N 75.11486°W / 39.94059; -75.11486
From Wikipedia, the free encyclopedia
The Coriell Institute for Medical Research
Established1953; 71 years ago (1953)
Focushuman genome
President and CEOJean-Pierre Issa
Key peopleLewis L. Coriell
Address403 Haddon Avenue, Camden, New Jersey, U.S.
Location
Camden, New Jersey, U.S.
Websitewww.coriell.org/

The Coriell Institute for Medical Research is an independent, non-profit biomedical research center dedicated to the study of the human genome. Coriell features programs in biobanking, personalized medicine, cell biology, cytogenetics, genotyping, and induced pluripotent stem cell science.[1] Located in downtown Camden, New Jersey, the Institute has partnered with several prominent state and national health leaders, including Cooper University Hospital, the Cooper Medical School of Rowan University, the United States Air Force, the University of Pennsylvania, and Stanford University.[2]

History

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Coriell Institute was chartered in 1953 as the South Jersey Medical Research Foundation Laboratory and constructed facilities in 1956. The laboratory was later named for director Lewis L. Coriell, who had worked at the Camden Municipal Hospital and developed aseptic tissue culture techniques that ultimately allowed poliovirus to be grown in culture. Dr. Coriell also led the field trials for the resulting vaccine.[3][4]

Operations

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Biobanking

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Regarded as one of the most diverse sources of cell lines and DNA available to the international research community, the Coriell Biorepositories maintain longstanding contracts with the National Institutes of Health and houses several significant collections, including the National Institute of General Medical Sciences Human Genetic Cell Repository, the National Institute of Neurological Disorders and Stroke Human Genetics DNA and Cell Line Repository, and the National Institute on Aging Cell Repository. The Institute houses cells for biotechnology companies and research foundations as well.[citation needed]

Research

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In 2018, Coriell partnered with Cooper University Health Care and the Cooper Medical School of Rowan University to form the Camden Opioid Research Initiative (CORI), a state-funded research project studying risk factors for opioid use disorder. CORI utilizes a three-pronged approach: a study of chronic pain patients, a study of patients currently being treated for opioid use disorder, and the creation of a novel biobank of biological specimens as a resource for addiction researchers.[5]

With these same partners, Coriell launched the Camden Cancer Research Center in 2023. Each of these three organizations has pledged an initial $1 million per year for 10 years, or a total of $30 million over 10 years, to investigate cancer and develop new therapies. [6]

Coriell also contributes to the precision medicine space with its innovative research study, the Coriell Personalized Medicine Collaborative (CPMC). Launched in 2007, the CPMC was a longitudinal initiative involving a network of physicians, scientists, genetic counselors, and hospital and academic partners. The study aims to explore the clinical utility of genetic information and returned individualized reports to nearly 8,000 volunteer participants detailing genetic and non-genetic risks for complex diseases.[7]

A spin-off company called Coriell Life Sciences was formed in January 2013 from a partnership between the Coriell Institute for Medical Research and IBM. The company offers full-service pharmacogenetics screening options to a range of different organizations.[8]

Services

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Coriell offers a diverse selection of services to customers and partners interested in outsourcing scientific work. Some of Coriell’s offered services include the creation of induced pluripotent stem cell lines, cell line authentication, cytogenetic analysis, DNA and RNA isolation, and public and private biobanking services.[citation needed]

Coriell’s quality management system has been certified to the latest ISO 9001:2015 standards.[9]

References

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  1. ^ "Coriell Institute for Medical Research". Coriell Institute for Medical Research. Retrieved 2014-06-06.
  2. ^ "CMSRU and Coriell Institute for Medical Research Build Educational Alliance - Cooper Medical School of Rowan University". Rowan.edu. Retrieved 2014-06-24.
  3. ^ O'Donnell, John M. (2002), Coriell: The Coriell Institute for Medical Research and a Half Century of Science, Science History Publications, ISBN 9780881352689
  4. ^ O'Connor, Anahad (July 2, 2001). "Lewis L. Coriell, 90, Virologist Who Set Stage for Polio Vaccine". Retrieved 2014-06-06.
  5. ^ Stainton, Lilo (30 Nov 2018). "Opioids: Unique Study of Genetic and Other Links to Addiction". www.njspotlight.com. Retrieved 11 Apr 2019.
  6. ^ "Cooper, Rowan, and Coriell to jointly run a new cancer research center in Camden".
  7. ^ "About the CPMC Study - Coriell Personalized Medicine Collaborative".
  8. ^ Young Rojahn, Susan (19 Feb 2013). "The Bank Where Doctors Can Stash Your Genome". www.technologyreview.com. Retrieved 14 Dec 2014.
  9. ^ "Coriell Institute for Medical Research Quality Management Earns Updated ISO 9001:2015 Certification".
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39°56′26″N 75°06′53″W / 39.94059°N 75.11486°W / 39.94059; -75.11486

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