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Colon cancer associated transcript 1

From Wikipedia, the free encyclopedia
CCAT1
Identifiers
AliasesCCAT1, CARLo-5, onco-lncRNA-40, colon cancer associated transcript 1 (non-protein coding), CARLO5, colon cancer associated transcript 1
External IDsOMIM: 617705; GeneCards: CCAT1; OMA:CCAT1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed search[1]n/a
Wikidata
View/Edit Human

Colon cancer associated transcript 1 is a long non-coding RNA that, in humans, is encoded by the CCAT1 gene.[2][3]

This gene produces a long non-coding RNA that promotes tumor formation and is upregulated in colon cancer and other cancer cell types.[4] This transcript may regulate long range chromosomal interactions, including at the Myc oncoprotein locus.[5] This RNA may also function as a molecular sponge for microRNAs.[6]

References

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  1. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. ^ "Entrez Gene: Colon cancer associated transcript 1 (non-protein coding)". Retrieved 2017-03-16.
  3. ^ "CCAT2 colon cancer associated transcript 2 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-06-13.
  4. ^ "CCAT1 Gene - GeneCards | CCAT1 RNA Gene". www.genecards.org. Retrieved 2020-06-29.
  5. ^ "CCAT1 colon cancer associated transcript 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2020-06-29.
  6. ^ "CCAT1 Gene - GeneCards | CCAT1 RNA Gene". www.genecards.org. Retrieved 2020-06-29.

Further reading

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