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Carotenoid 1,2-hydratase

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Carotenoid 1,2-hydratase
Identifiers
EC no.4.2.1.131
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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Carotenoid 1,2-hydratase (EC 4.2.1.131, CrtC) is an enzyme with systematic name lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming).[1][2] This enzyme catalyses the following chemical reaction

(1) 1-hydroxy-1,2-dihydrolycopene lycopene + H2O
(2) 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene 1-hydroxy-1,2-dihydrolycopene + H2O

In Rubrivivax gelatinosus and Thiocapsa roseopersicina both products are formed.

References

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  1. ^ Steiger S, Mazet A, Sandmann G (June 2003). "Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus". Archives of Biochemistry and Biophysics. 414 (1): 51–8. doi:10.1016/s0003-9861(03)00099-7. PMID 12745254.
  2. ^ Hiseni A, Arends IW, Otten LG (August 2011). "Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina". Applied Microbiology and Biotechnology. 91 (4): 1029–36. doi:10.1007/s00253-011-3324-1. PMC 3145076. PMID 21590288.
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