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COG3860 RNA motif

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COG3860
Consensus secondary structure and sequence conservation of COG3860 RNA
Identifiers
SymbolCOG3860
RfamRF02940
Other data
RNA typeCis-reg
SOSO:0005836
PDB structuresPDBe

The COG3860 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] COG3860 motifs are found in Alphaproteobacteria, Betaproteobacteria, and Thermodesulfobacteriota. Energetically stable tetraloops often occur in this motif.

COG3860 motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. Unfortunately the functions of the putatively regulated genes are not sufficiently well known to be able to hypothesize a biological function for COG3860 RNAs.

References

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  1. ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.