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Protein-coding gene in humans
CDGSH iron sulfur domain 2 is a protein that in humans is encoded by the CISD2 gene .[ 5]
The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum . The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis . Defects in this gene are a cause of Wolfram syndrome 2 . [provided by RefSeq, Mar 2011].
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This article incorporates text from the United States National Library of Medicine , which is in the public domain .