CHPF

CHPF
Identifiers
Aliases	CHPF, CHSY2, CSS2, chondroitin polymerizing factor
External IDs	OMIM: 610405; MGI: 106576; HomoloGene: 11574; GeneCards: CHPF; OMA:CHPF - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	219,543,809 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	75,455,951 bp
RNA expression pattern
	Top expressed in
	decidua; ; anterior pituitary; ; stromal cell of endometrium; ; apex of heart; ; right auricle; ; ascending aorta; ; left ovary; ; body of pancreas; ; right ovary; ; right coronary artery;
	Top expressed in
	CA3 field; ; primary visual cortex; ; superior frontal gyrus; ; perirhinal cortex; ; entorhinal cortex; ; ankle joint; ; lactiferous gland; ; dentate gyrus of hippocampal formation granule cell; ; choroid plexus of fourth ventricle; ; yolk sac;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; acetylgalactosaminyltransferase activity; protein binding; metal ion binding; glycosyltransferase activity; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;
Cellular component	cytoplasm; integral component of membrane; Golgi cisterna membrane; cytosol; Golgi membrane; mitochondrial matrix; Golgi apparatus; mitochondrion; membrane;
Biological process	chondroitin sulfate biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	79586
	74241
	ENSG00000123989
	ENSMUSG00000032997
	Q8IZ52
	Q6IQX7
	NM_001195731; NM_024536
	NM_001001565; NM_001001566
	NP_001182660; NP_078812
	NP_001001565; NP_001001566
	Wikidata
View/Edit Human	View/Edit Mouse

Chondroitin sulfate synthase 2 is an enzyme that in humans is encoded by the CHPF gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000123989 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032997 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
^ Kitagawa H, Izumikawa T, Uyama T, Sugahara K (Jun 2003). "Molecular cloning of a chondroitin polymerizing factor that cooperates with chondroitin synthase for chondroitin polymerization". J Biol Chem. 278 (26): 23666–71. doi:10.1074/jbc.M302493200. PMID 12716890.
^ "Entrez Gene: CHPF chondroitin polymerizing factor".

External links

Human CHPF genome location and CHPF gene details page in the UCSC Genome Browser.

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yada T, Gotoh M, Sato T, et al. (2003). "Chondroitin sulfate synthase-2. Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities". J. Biol. Chem. 278 (32): 30235–47. doi:10.1074/jbc.M303657200. PMID 12761225.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000123989 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032997 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11230166-5] Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.

[pmid12716890-6] Kitagawa H, Izumikawa T, Uyama T, Sugahara K (Jun 2003). "Molecular cloning of a chondroitin polymerizing factor that cooperates with chondroitin synthase for chondroitin polymerization". J Biol Chem. 278 (26): 23666–71. doi:10.1074/jbc.M302493200. PMID 12716890.

[entrez-7] "Entrez Gene: CHPF chondroitin polymerizing factor".

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[2]

[3]

[4]

[5]

[6]

[7]

References

External links

Further reading