Bisdemethoxycurcumin
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| Names | |
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| Preferred IUPAC name
(1E,6E)-1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione | |
| Other names
Curcumin III, bis(4-hydroxycinnamoyl)methane, didemethoxycurcumin, bisdemethoxycurcumin, Bis(p-hydroxycinnamoyl)methane, NSC687839
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C19H16O4 | |
| Molar mass | 308.333 g·mol−1 |
| Density | 1.285 g/cm3 |
| Melting point | 226 to 231 °C (439 to 448 °F; 499 to 504 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Bisdemethoxycurcumin is a curcuminoid found (along with the curcuminoids curcumin and demethoxycurcumin) in turmeric (Curcuma longa), but absent in Javanese turmeric (Curcuma xanthorrhiza).[1] Bisdemethoxycurcumin is used as a pigment and nutraceutical with antimutagenic properties.[2][3] All three of the curcuminoids found in Curcuma longa have been shown to have antioxidant properties, but bisdemethoxycurcumin is more resistant than the others to alkaline degradation.[4] It was found to be effective in sensitizing PC cells resistance against gemcitabine.[5]
See also
[edit]References
[edit]- ^ T. K. Lim (11 February 2016). Edible Medicinal and Non-Medicinal Plants: Volume 12 Modified Stems, Roots, Bulbs. Springer. p. 374. ISBN 978-3-319-26065-5.
- ^ Hajime Ohigashi; Toshihiko Osawa; Junji Terao; Shaw Watanabe; Toshikazu Yoshikawa (27 November 2013). Food Factors for Cancer Prevention. Springer Science & Business Media. p. 251. ISBN 978-4-431-67017-9.
- ^ Jun-Ping Xu (25 November 2016). Cancer Inhibitors from Chinese Natural Medicines. CRC Press. p. 338. ISBN 978-1-4987-8766-6.
- ^ Francisco Delgado-Vargas; Octavio Paredes-Lopez (26 December 2002). Natural Colorants for Food and Nutraceutical Uses. CRC Press. p. 244. ISBN 978-1-4200-3171-3.
- ^ "Bisdemethoxycurcumin". ScienceDirect. ScienceDirect. Retrieved 5 October 2022.
External links
[edit]- "TY000079". MassBank. MassBank Project. Archived from the original on 8 December 2015. Retrieved 3 May 2012.
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