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Birgit Derntl

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Birgit Derntl
Born
Austria
NationalityAustrian
Alma materUniversity of Vienna
Scientific career
FieldsNeuroscience, Psychology & Psychotherapy
InstitutionsUniversity of Vienna
Medical University of Vienna
RWTH Aachen University
University of Tübingen
Thesis (2006)
Doctoral advisorIlse Kryspin-Exner
Ewald Moser
Websitehttps://www.medizin.uni-tuebingen.de/de/das-klinikum/mitarbeiter/profil/1610

Birgit Derntl is an Austrian clinical psychologist and psychotherapist. Birgit Derntl is Professor (W3) for Women’s Mental Health & Brain Function in the Department of Psychiatry and Psychotherapy at the Tübingen Center for Mental Health, University of Tübingen, Germany.

Education

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Birgit Derntl studied psychology (Diplom) at the University of Vienna. She obtained her doctorate (Dr. rer. nat.) in Psychology (summa cum laude) from the University of Vienna, Austria, in 2006, under the mentorship of Ilse Kryspin-Exner and Ewald Moser. As a graduate student she investigated the role of the amygdala for explicit emotion recognition and studied the effects of ethnic group as well as sex hormone profile at the MR Center of Excellence affiliated with the Medical University of Vienna and the University of Vienna from 2004 to 2006. After completing her doctoral studies, she joined RWTH Aachen University as a postdoctoral research fellow of the International Research Training Group 1328 Schizophrenia and Autism. She returned to the University of Vienna in 2009 where Derntl completed her (Habilitation) in 2012.

Research Interests

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She is a full Professor for Women's Mental Health & Brain Function, investigating the nuanced influences of sex/gender and sex hormones on behavior, brain architecture, and mental health. Derntl's research interests lie at the intersection of social and affective neuroscience, with an emphasis on sex/gender differences in association with sex steroids. She began with emotion processing and recognition,[1][2][3][4][5] moving on to investigating empathy, where she showed sex/gender differences.[6] She further showed that empathic abilities are impaired in individuals diagnosed with schizophrenia[7] also in comparison with other clinical groups[8][9] and in individuals with ultra-high risk of psychosis.[10][11] In depressed individuals, Derntl reported sex/gender differences in approach and avoidance behavior,[12][13] as well as causal attribution and emotion regulation.[14]

Her most recent work focuses on women’s mental health, exploring the influence of hormonal transition periods and hormonal therapy on mental health, brain function, and architecture.[15][16][17][18] She found that estradiol administration affects brain function[15][16] and effective connectivity[19] in naturally cycling females. She also demonstrated that intake of oral contraception affects empathic behavior and the underlying neural networks[20] and reported sex/gender differences in stress reactivity in women and men.[21] Together with colleagues at the University of Tübingen, Derntl is exploring the nuanced complexities of sex/gender differences within the realm of neuroscience.[22] Her work has been broadly cited on numerous topics, such as Depressive realism, Self-serving bias, Causes of gender incongruence, Neuroscience and sexual orientation, Combined hormonal contraception, and Anger.

She is involved in the steering boards of prominent research centers, such as the "Tübingen Center for Mental Health" as part of the German Center for Mental Health (DZPG). Since 2023, Derntl has served[23] as co-spokesperson of the International Research Training Group (IRTG 2804) “Women’s Mental Health across the Reproductive Years” – a collaboration with colleagues from Uppsala University, Sweden.

Derntl’s work has been supported by the Deutsche Forschungsgemeinschaft (DFG), Fonds zur Förderung der wissenschaftlichen Forschung (FWF) and the Federal Ministry of Education and Science (BMBF).

Career

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In 2011, Derntl was appointed Assistant Professor for Translational Neuroscience in Psychiatry and Neurology at RWTH Aachen University, Germany. In 2015, she was appointed Full Professor (W3) at the Department of General Psychiatry and Psychotherapy, University of Tübingen, Germany. She continues her neuroscientific research in the field of mental health. Derntl actively contributes to advancing research in various capacities, including editorial roles, board memberships, and organizing academic events.

Awards

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Birgit Derntl has received several awards and honors throughout her career.

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References

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  1. ^ Derntl, Birgit; Windischberger, Christian; Robinson, Simon; Lamplmayr, Elisabeth; Kryspin-Exner, Ilse; Gur, Ruben C.; Moser, Ewald; Habel, Ute (September 2008). "Facial emotion recognition and amygdala activation are associated with menstrual cycle phase". Psychoneuroendocrinology. 33 (8): 1031–1040. doi:10.1016/j.psyneuen.2008.04.014. ISSN 0306-4530. PMC 7437605. PMID 18675521.
  2. ^ Derntl, Birgit; Kryspin-Exner, Ilse; Fernbach, Eva; Moser, Ewald; Habel, Ute (January 2008). "Emotion recognition accuracy in healthy young females is associated with cycle phase". Hormones and Behavior. 53 (1): 90–95. doi:10.1016/j.yhbeh.2007.09.006. ISSN 0018-506X. PMID 17976599.
  3. ^ Derntl, Birgit; Seidel, Eva-Maria; Kryspin-Exner, Ilse; Hasmann, Alexander; Dobmeier, Matthias (November 2009). "Facial emotion recognition in patients with bipolar I and bipolar II disorder". The British Journal of Clinical Psychology. 48 (Pt 4): 363–375. doi:10.1348/014466509X404845. ISSN 0144-6657. PMID 19220936.
  4. ^ Derntl, Birgit; Habel, Ute; Windischberger, Christian; Robinson, Simon; Kryspin-Exner, Ilse; Gur, Ruben C.; Moser, Ewald (2009-08-04). "General and specific responsiveness of the amygdala during explicit emotion recognition in females and males". BMC Neuroscience. 10: 91. doi:10.1186/1471-2202-10-91. ISSN 1471-2202. PMC 2728725. PMID 19653893.
  5. ^ Derntl, Birgit; Windischberger, Christian; Robinson, Simon; Kryspin-Exner, Ilse; Gur, Ruben C.; Moser, Ewald; Habel, Ute (June 2009). "Amygdala activity to fear and anger in healthy young males is associated with testosterone". Psychoneuroendocrinology. 34 (5): 687–693. doi:10.1016/j.psyneuen.2008.11.007. ISSN 1873-3360. PMID 19136216.
  6. ^ Derntl, Birgit; Finkelmeyer, Andreas; Eickhoff, Simon; Kellermann, Thilo; Falkenberg, Dania I.; Schneider, Frank; Habel, Ute (January 2010). "Multidimensional assessment of empathic abilities: neural correlates and gender differences". Psychoneuroendocrinology. 35 (1): 67–82. doi:10.1016/j.psyneuen.2009.10.006. ISSN 1873-3360. PMID 19914001.
  7. ^ Derntl, Birgit; Finkelmeyer, Andreas; Toygar, Timur K.; Hülsmann, Anna; Schneider, Frank; Falkenberg, Dania I.; Habel, Ute (March 2009). "Generalized deficit in all core components of empathy in schizophrenia". Schizophrenia Research. 108 (1–3): 197–206. doi:10.1016/j.schres.2008.11.009. PMID 19087898.
  8. ^ Derntl, Birgit; Finkelmeyer, Andreas; Voss, Bianca; Eickhoff, Simon B.; Kellermann, Thilo; Schneider, Frank; Habel, Ute (April 2012). "Neural correlates of the core facets of empathy in schizophrenia". Schizophrenia Research. 136 (1–3): 70–81. doi:10.1016/j.schres.2011.12.018. ISSN 1573-2509. PMC 7988185. PMID 22306196.
  9. ^ Derntl, Birgit; Seidel, Eva-Maria; Schneider, Frank; Habel, Ute (December 2012). "How specific are emotional deficits? A comparison of empathic abilities in schizophrenia, bipolar and depressed patients". Schizophrenia Research. 142 (1–3): 58–64. doi:10.1016/j.schres.2012.09.020. ISSN 1573-2509. PMC 3514634. PMID 23116884.
  10. ^ Regenbogen, Christina; Kellermann, Thilo; Seubert, Janina; Schneider, Daniel A.; Gur, Raquel E.; Derntl, Birgit; Schneider, Frank; Habel, Ute (March 2015). "Neural responses to dynamic multimodal stimuli and pathology-specific impairments of social cognition in schizophrenia and depression". The British Journal of Psychiatry: The Journal of Mental Science. 206 (3): 198–205. doi:10.1192/bjp.bp.113.143040. ISSN 1472-1465. PMID 25573396.
  11. ^ Derntl, Birgit; Michel, Tanja Maria; Prempeh, Pamela; Backes, Volker; Finkelmeyer, Andreas; Schneider, Frank; Habel, Ute (November 2015). "Empathy in individuals clinically at risk for psychosis: brain and behaviour". The British Journal of Psychiatry: The Journal of Mental Science. 207 (5): 407–413. doi:10.1192/bjp.bp.114.159004. ISSN 1472-1465. PMID 26294367.
  12. ^ Seidel, Eva-Maria; Habel, Ute; Finkelmeyer, Andreas; Hasmann, Alexander; Dobmeier, Matthias; Derntl, Birgit (March 2012). "Risk or resilience? Empathic abilities in patients with bipolar disorders and their first-degree relatives". Journal of Psychiatric Research. 46 (3): 382–388. doi:10.1016/j.jpsychires.2011.11.006. ISSN 1879-1379. PMID 22133461.
  13. ^ Derntl, Birgit; Seidel, Eva-Maria; Eickhoff, Simon B.; Kellermann, Thilo; Gur, Ruben C.; Schneider, Frank; Habel, Ute (2011). "Neural correlates of social approach and withdrawal in patients with major depression". Social Neuroscience. 6 (5–6): 482–501. doi:10.1080/17470919.2011.579800. ISSN 1747-0927. PMC 3203307. PMID 21777105.
  14. ^ Radke, Sina; Hoffstaedter, Felix; Löffler, Leonie; Kogler, Lydia; Schneider, Frank; Blechert, Jens; Derntl, Birgit (February 2018). "Imaging the up's and down's of emotion regulation in lifetime depression". Brain Imaging and Behavior. 12 (1): 156–167. doi:10.1007/s11682-017-9682-2. ISSN 1931-7565. PMID 28197859.
  15. ^ a b Rehbein, Elisa; Hornung, Jonas; Sundström Poromaa, Inger; Derntl, Birgit (2021). "Shaping of the Female Human Brain by Sex Hormones: A Review". Neuroendocrinology. 111 (3): 183–206. doi:10.1159/000507083. ISSN 1423-0194. PMID 32155633.
  16. ^ a b Rehbein, Elisa; Kogler, Lydia; Hornung, Jonas; Morawetz, Carmen; Bayer, Janine; Krylova, Marina; Sundström-Poromaa, Inger; Derntl, Birgit (2021-09-23). "Estradiol administration modulates neural emotion regulation". Psychoneuroendocrinology. 134: 105425. doi:10.1016/j.psyneuen.2021.105425. ISSN 1873-3360. PMID 34607175.
  17. ^ Sacher, Julia; Chechko, Natalia; Dannlowski, Udo; Walter, Martin; Derntl, Birgit (October 2020). "The peripartum human brain: Current understanding and future perspectives". Frontiers in Neuroendocrinology. 59: 100859. doi:10.1016/j.yfrne.2020.100859. ISSN 1095-6808. PMID 32771399.
  18. ^ Dubol, Manon; Epperson, C. Neill; Sacher, Julia; Pletzer, Belinda; Derntl, Birgit; Lanzenberger, Rupert; Sundström-Poromaa, Inger; Comasco, Erika (January 2021). "Neuroimaging the menstrual cycle: A multimodal systematic review". Frontiers in Neuroendocrinology. 60: 100878. doi:10.1016/j.yfrne.2020.100878. ISSN 1095-6808. PMID 33098847.
  19. ^ Derntl, Birgit; Eber, Corinna H.; Kogler, Lydia; Rehbein, Elisa; Sundstöm-Poromaa, Inger; Morawetz, Carmen (September 2024). "Estradiol modulates changes in effective connectivity in emotion regulation networks". Psychoneuroendocrinology. 167: 107103. doi:10.1016/j.psyneuen.2024.107103. ISSN 1873-3360. PMID 38924828.
  20. ^ Kimmig, Ann-Christin Sophie; Wildgruber, Dirk; Gärtner, Anna; Drotleff, Bernhard; Krylova, Marina; Lämmerhofer, Michael; Sundström-Poromaa, Inger; Derntl, Birgit (2023-04-04). "Lower affective empathy in oral contraceptive users: a cross-sectional fMRI study". Cerebral Cortex (New York, N.Y.: 1991). 33 (8): 4319–4333. doi:10.1093/cercor/bhac345. ISSN 1460-2199. PMID 36137568.
  21. ^ Kogler, Lydia; Seidel, Eva-Maria; Metzler, Hannah; Thaler, Hanna; Boubela, Roland N.; Pruessner, Jens C.; Kryspin-Exner, Ilse; Gur, Ruben C.; Windischberger, Christian; Moser, Ewald; Habel, Ute; Derntl, Birgit (2017-12-08). "Impact of self-esteem and sex on stress reactions". Scientific Reports. 7 (1): 17210. doi:10.1038/s41598-017-17485-w. ISSN 2045-2322. PMC 5722874. PMID 29222516.
  22. ^ Derntl, Birgit; Hage, Steffen R.; Hallschmid, Manfred (March 2024). "Making Sense of Sex in Neuroscience". Biological Psychiatry Global Open Science. 4 (2): 100292. doi:10.1016/j.bpsgos.2024.100292. ISSN 2667-1743. PMC 10945429. PMID 38501116.
  23. ^ "People IRTG – IRTG 2804" (in German). Retrieved 2024-09-26.
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