Biotin-dependent malonate decarboxylase
| Biotin-dependent malonate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.1.1.89 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Biotin-dependent malonate decarboxylase (EC 4.1.1.89, malonate decarboxylase (with biotin), malonate decarboxylase) is an enzyme with systematic name malonate carboxy-lyase (biotin-dependent).[1][2][3][4][5][6][7] This enzyme catalyses the following chemical reaction
Two types of malonate decarboxylase are currently known, both of which form multienzyme complexes.
References
[edit]- ^ Hilbi H, Dehning I, Schink B, Dimroth P (July 1992). "Malonate decarboxylase of Malonomonas rubra, a novel type of biotin-containing acetyl enzyme". European Journal of Biochemistry. 207 (1): 117–23. doi:10.1111/j.1432-1033.1992.tb17028.x. PMID 1628643.
- ^ Hilbi H, Dimroth P (1994). "Purification and characterization of a cytoplasmic enzyme component of the Na+-activated malonate decarboxylase system of Malonomonas rubra: acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase". Archives of Microbiology. 162 (1–2): 48–56. doi:10.1007/bf00264372. PMID 18251085.
- ^ Berg M, Hilbi H, Dimroth P (April 1996). "The acyl carrier protein of malonate decarboxylase of Malonomonas rubra contains 2'-(5"-phosphoribosyl)-3'-dephosphocoenzyme A as a prosthetic group". Biochemistry. 35 (15): 4689–96. doi:10.1021/bi952873p. PMID 8664258.
- ^ Berg M, Hilbi H, Dimroth P (April 1997). "Sequence of a gene cluster from Malonomonas rubra encoding components of the malonate decarboxylase Na+ pump and evidence for their function". European Journal of Biochemistry. 245 (1): 103–15. doi:10.1111/j.1432-1033.1997.00103.x. PMID 9128730.
- ^ Micklefield J, Harris KJ, Gröger S, Mocek U, Hilbi H, Dimroth P, Floss HG (1995). "Stereochemical course of malonate decarboxylase in Malonomonas rubra has biotin decarboxylation with retention". J. Am. Chem. Soc. 117 (3): 1153–1154. doi:10.1021/ja00108a042.
- ^ Kim YS (September 2002). "Malonate metabolism: biochemistry, molecular biology, physiology, and industrial application". Journal of Biochemistry and Molecular Biology. 35 (5): 443–51. doi:10.5483/bmbrep.2002.35.5.443. PMID 12359084.
- ^ Dimroth P, Hilbi H (July 1997). "Enzymic and genetic basis for bacterial growth on malonate". Molecular Microbiology. 25 (1): 3–10. doi:10.1046/j.1365-2958.1997.4611824.x. PMID 11902724.
External links
[edit]- Biotin-dependent+malonate+decarboxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
