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Baruol synthase

From Wikipedia, the free encyclopedia
Baruol synthase
Identifiers
EC no.5.4.99.57
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Baruol synthase (EC 5.4.99.57, BARS1) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baruol-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene baruol

The enzyme from Arabidopsis thaliana also produces traces of 22 other triterpenoids.

References

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  1. ^ Lodeiro S, Xiong Q, Wilson WK, Kolesnikova MD, Onak CS, Matsuda SP (September 2007). "An oxidosqualene cyclase makes numerous products by diverse mechanisms: a challenge to prevailing concepts of triterpene biosynthesis". Journal of the American Chemical Society. 129 (36): 11213–22. doi:10.1021/ja073133u. PMID 17705488.
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