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Barbara A. Horwitz

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Barbara A. Horwitz
Alma mater
  • University of Florida
  • Emory University
Awards
  • Lifetime Mentor Award from the American Association for the Advancement of Science
  • Distinguished Scientist of the Society for Experimental Biology & Medicine
Scientific career
Fieldsphysiology, nutritional science, metabolism, pharmacology, neurobiology
InstitutionsUniversity of California, Davis
Websitehttps://biology.ucdavis.edu/people/barbara-horwitz

Barbara A. Horwitz is an American cellular physiologist whose work focuses on metabolism. In particular, her research has centered on the neural and hormonal regulation of energy balance.

Horwitz joined the University of California, Davis first as a postdoctoral scholar and then as an Assistant Professor. Her teaching, mentorship and leadership in supporting historically marginalized communities in academia have earned her numerous campus and national awards.[1]

Education and early life

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After obtaining her B.S. in biology with highest honors (1961) and an M.S. in biology (1962) from the University of Florida, Horwitz pursued a Ph.D. in physiology at Emory University in 1966.[2] She then pursued postdoctoral work at the University of California, Los Angeles on a fellowship in physiology. In 1972, she joined UC Davis faculty as an Assistant Professor and was later promoted to Professor in 1978. In 1991, Horwitz became Chair of the Department of Animal Physiology in the Division of Biological Sciences and became the first woman to receive the UC Davis Prize for Teaching and Scholarly Achievement.[3] When this department transformed into the Section of Neurobiology, Physiology, and Behavior in 1993, she served as its first Chair.[2]

Research

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Horwitz has published over 200 research articles across a diverse range of scientific fields including: physiology, nutritional science, neurobiology, pharmacology, and metabolism.[4] She is well known for her research on brown adipose tissue and its major roles in thermogenesis during hibernation [5] and senescence.[6] Much of her lab's research has been focused on elucidating the underlying genetic, neuronal, and hormonal processes that regulate mammalian thermogenesis[7][8][9] and hibernation.[10][11] In addition, Horwitz and collaborators have conducted studies on the cellular mechanisms involved in obesity,[12][13] neuroplasticity,[14][15] and aging.[16][17]

Major contributions to science and academia

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Horwitz is the co-director of the Initiative for Maximizing Student Development (IMSD) Program at UC Davis which supports underrepresented minority graduate students pursuing Ph.D.'s in the biomedical and behavioral sciences.[18] This program, funded by the National Institutes of Health (NIH),[19] serves to create a more diverse pool of emerging scientists and helps underrepresented minority graduate students develop the professional skills necessary to successfully enter their respective fields.[20] In addition, Horwitz also served as the vice provost for Academic Personnel at UC Davis from 2001 to 2007, Interim Provost and Executive Chancellor from 2007 to 2009, and vice provost for Academic Personnel from 2009 to 2011.[21] During that time, she helped develop and launch the MyInfoVault (MIV) Academic Affairs database which consolidates academic personnel information in order to streamline processing and review.[22] Horwitz has consistently been an advocate for junior faculty members at UC Davis and has actively worked to demystify the systems within academia by creating an online frequently asked questions page to help guide new faculty members through their academic careers.[23] In recognition of her numerous contributions to UC Davis, a tribute to Horwitz was given at the Spring New-Emeriti Distinguished Lectures series in 2023. She has also served as President of both the American Physiology Society and the Society for Experimental Biology and Medicine (SEBM), and is an elected fellow of the American Association for the Advancement of Science (AAAS) and the American Physiology Society.[24]

Awards and recognition

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  • Lifetime Mentor Award from the American Association for the Advancement of Science (2015)[25]
  • Chancellor's Achievement Awards for Diversity and Community (2014)[26]
  • Ray G. Daggs Award, American Physiological Society (2012)[27]
  • Distinguished Scientist of the Society for Experimental Biology & Medicine (2010)[28]
  • Bodil Schmidt-Nielson Distinguished Mentor and Scientist Award (2007)[29]
  • President, American Physiological Society (2002–03)[30]
  • President, Society for Experimental Biology and Medicine (2001–03)[31]
  • American Physiological Society Arthur C. Guyton Physiology Teacher of the Year (1996)[32]
  • University of California Presidential Award for Excellence in Fostering Undergraduate Research (1995)[33]
  • UC Davis Prize for Teaching & Scholarly Achievement (1991)[33]
  • Academic Senate Distinguished Teaching Award, UC Davis (1982)[34]

References

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  1. ^ "Barbara A. Horwitz and John M. Horowitz Undergraduate Research Awards". Default. Retrieved 2023-04-08.
  2. ^ a b "2007Media Guide WSOC (PDF)" (PDF). UC Davis Athletics. Retrieved 2023-04-08.
  3. ^ Anonymous (2017-06-28). "Faculty Memberships and Awards". College of Biological Sciences. Retrieved 2023-04-13.
  4. ^ "Barbara A Horwitz | UC Davis Profiles". profiles.ucdavis.edu. Retrieved 2023-04-09.
  5. ^ Smith, R E; Horwitz, B A (1969). "Brown fat and thermogenesis". Physiological Reviews. 49 (2): 330–425. doi:10.1152/physrev.1969.49.2.330. ISSN 0031-9333. PMID 4888392.
  6. ^ McDonald, R. B.; Horwitz, B. A. (1999). "Brown adipose tissue thermogenesis during aging and senescence". Journal of Bioenergetics and Biomembranes. 31 (5): 507–516. doi:10.1023/a:1005404708710. ISSN 0145-479X. PMID 10653478. S2CID 38254662.
  7. ^ Horwitz, B. A.; Horowitz, J. M.; Smith, R. Em. (1969). "Norepinephrine-Induced Depolarization of Brown Fat Cells". Proceedings of the National Academy of Sciences. 64 (1): 113–120. Bibcode:1969PNAS...64..113H. doi:10.1073/pnas.64.1.113. ISSN 0027-8424. PMC 286134. PMID 5262992.
  8. ^ Flaim, K. E.; Horwitz, B. A.; Horowitz, J. M. (1977). "Coupling of signals to brown fat: alpha- and beta-adrenergic responses in intact rats". The American Journal of Physiology. 232 (3): R101–109. doi:10.1152/ajpregu.1977.232.3.R101. ISSN 0002-9513. PMID 842692.
  9. ^ Florez-Duquet, M.; Horwitz, B. A.; McDonald, R. B. (1998). "Cellular proliferation and UCP content in brown adipose tissue of cold-exposed aging Fischer 344 rats". The American Journal of Physiology. 274 (1): R196–203. doi:10.1152/ajpregu.1998.274.1.R196. ISSN 0002-9513. PMID 9458918.
  10. ^ Arant, Ryan J.; Goo, Marisa S.; Gill, Phoebe D.; Nguyen, Yen; Watson, Katherine D.; Hamilton, Jock S.; Horowitz, John M.; Horwitz, Barbara A. (2011). "Decreasing temperature shifts hippocampal function from memory formation to modulation of hibernation bout duration in Syrian hamsters". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301 (2): R438–R447. doi:10.1152/ajpregu.00016.2011. ISSN 0363-6119. PMID 21562095.
  11. ^ Horwitz, Barbara A.; Chau, Sat M.; Hamilton, Jock S.; Song, Christine; Gorgone, Julia; Saenz, Marissa; Horowitz, John M.; Chen (陳昭吟), Chao-Yin (2013-10-01). "Temporal relationships of blood pressure, heart rate, baroreflex function, and body temperature change over a hibernation bout in Syrian hamsters". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 305 (7): R759–R768. doi:10.1152/ajpregu.00450.2012. ISSN 0363-6119. PMC 3798792. PMID 23904107.
  12. ^ Freedman, M. R.; Horwitz, B. A.; Stern, J. S. (1986). "Effect of adrenalectomy and glucocorticoid replacement on development of obesity". The American Journal of Physiology. 250 (4 Pt 2): R595–607. doi:10.1152/ajpregu.1986.250.4.R595. ISSN 0002-9513. PMID 3515971.
  13. ^ Warren, L. E.; Horwitz, B. A.; Hamilton, J. S.; Fuller, C. A. (2001). "Effects of 2 G on adiposity, leptin, lipoprotein lipase, and uncoupling protein-1 in lean and obese Zucker rats". Journal of Applied Physiology. 90 (2): 606–614. doi:10.1152/jappl.2001.90.2.606. ISSN 8750-7587. PMID 11160060.
  14. ^ Hamilton, Jock S.; Chau, Sat M.; Malins, Kevin J.; Ibanez, Giancarlo G.; Horowitz, John M.; Horwitz, Barbara A. (2017). "Syrian hamster neuroplasticity mechanisms fail as temperature declines to 15 °C, but histaminergic neuromodulation persists". Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology. 187 (5–6): 779–791. doi:10.1007/s00360-017-1078-5. ISSN 1432-136X. PMID 28391591. S2CID 253884699.
  15. ^ Horowitz, John M.; Horwitz, Barbara A. (2019). "Extreme Neuroplasticity of Hippocampal CA1 Pyramidal Neurons in Hibernating Mammalian Species". Frontiers in Neuroanatomy. 13: 9. doi:10.3389/fnana.2019.00009. ISSN 1662-5129. PMC 6381046. PMID 30814935.
  16. ^ Asami, Danny K.; McDonald, Roger B.; Hagopian, Kevork; Horwitz, Barbara A.; Warman, David; Hsiao, Aileen; Warden, Craig; Ramsey, Jon J. (2008-12-01). "Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice". Experimental Gerontology. 43 (12): 1069–1076. doi:10.1016/j.exger.2008.09.010. ISSN 0531-5565. PMC 2614627. PMID 18852040.
  17. ^ McDonald, Roger B.; Walker, Keya M.; Warman, David B.; Griffey, Stephen M.; Warden, Craig H.; Ramsey, Jon J.; Horwitz, Barbara A. (2008). "Characterization of survival and phenotype throughout the life span in UCP2/UCP3 genetically altered mice". Experimental Gerontology. 43 (12): 1061–1068. doi:10.1016/j.exger.2008.09.011. ISSN 1873-6815. PMID 18854208. S2CID 20274848.
  18. ^ "People | Initiative for Maximizing Student Development (IMSD) Program". imsd.ucdavis.edu. Retrieved 2023-04-03.
  19. ^ "National Institute of General Medical Sciences". National Institute of General Medical Sciences (NIGMS). Retrieved 2023-04-03.
  20. ^ Gomes, Aldrin (2018-04-27). "Program Information". Initiative for Maximizing Student Development (IMSD) Program. Retrieved 2023-04-03.
  21. ^ "Chancellor Honors 7 for Achievement in Diversity and Community - RESOURCEpublic". www.gk-12-resource-ucdavis.org. Retrieved 2023-04-09.
  22. ^ admin, Site Factory (2012-07-09). "MyInfoVault (MIV)". Academic Affairs. Retrieved 2023-04-09.
  23. ^ WebDev, I. E. T. (2011-02-11). "VP Horwitz to step down from Academic Personnel". UC Davis. Retrieved 2023-04-09.
  24. ^ "Barbara A. Horwitz and John M. Horowitz Undergraduate Research Awards". Default. Retrieved 2023-04-09.
  25. ^ WebDev, I. E. T. (2015-03-02). "LAURELS: Horwitz receives AAAS Lifetime Mentor Award". UC Davis. Retrieved 2023-04-03.
  26. ^ WebDev, I. E. T. (2014-02-25). "Chancellor honors 7 for achievement in diversity and community". UC Davis. Retrieved 2023-04-08.
  27. ^ "APS Council Holds Fall Council Meeting in Jacksonville, FL" (PDF). The Physiologist. 55 (1): 7. February 1012. Retrieved 2023-04-03.
  28. ^ "Distinguished Scientist". www.sebm.org. Retrieved 2023-04-03.
  29. ^ "Horwitz Receives Fourth Schmidt-Nielsen Distinguished Mentor and Scientist Award" (PDF). The Physiologist. 50 (1): 14. 2007. PMID 17366940. Retrieved 2023-04-03.
  30. ^ "Past Presidents". Default. Retrieved 2023-04-03.
  31. ^ "Past Officers". www.sebm.org. Retrieved 2023-04-03.
  32. ^ "Horwitz Receives 1996 Arthur C. Guyton Teacher of the Year Award" (PDF). The Physiologist. 39 (2): 56. April 1996. Retrieved 2023-04-03.
  33. ^ a b "Faculty Memberships and Awards". College of Biological Sciences. 2017-06-28. Retrieved 2023-04-03.
  34. ^ "Davis Division of the Academic Senate: Academic Award Recipients" (PDF). Retrieved 2023-04-03.
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