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Bacteroidales-2 RNA motif

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Bacteroidales-2
Consensus secondary structure and sequence conservation of Bacteroidales-2 RNA
Identifiers
SymbolBacteroidales-2
RfamRF02943
Other data
RNA typeGene; sRNA
SOSO:0001263
PDB structuresPDBe

The Bacteroidales-2 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] Bacteroidales-2 motifs are found in Bacteroidales. Bacteroidales-2 RNAs likely function in trans as sRNAs.

Bacteroidales-2 RNAs are relatively large compared to most other bacterial sRNAs, averaging just over 400 nucleotides. Despite this large size, Bacteriodales-2 RNAs exhibit a relatively simple secondary structure, being composed mainly of hairpins.

Bacteroidales-2 RNAs often occur adjacent to large regions that do not appear to encode proteins. A possible weak association with Mu-like phages was proposed. The hairpin on the 3' end of the Bacteroidales-2 motif might function as a Rho-independent transcription terminator.

References

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  1. ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.