B type inclusion

B-type inclusions, formerly known as Guarnieri bodies /ɡwɑːrnˈjɛəri/ are cellular features found upon microscopic inspection of epithelial cells of individuals suspected of having poxvirus^[1] (e.g. smallpox^[2] or vaccinia). In cells stained with eosin, they appear as pink blobs in the cytoplasm of affected epithelial cells. The absence of Guarnieri bodies cannot be used as to rule out smallpox, however, as more sensitive test need to be performed.

B-type inclusions are the sites of viral replication and are found in all poxvirus-infected cells, unlike A-type inclusions which are more strongly eosinophilic and only found in infections with certain poxviruses.^[3]

They are named after the Italian physician Giuseppe Guarnieri.

References

^ "Variola Virus". Archived from the original on 23 January 2009. Retrieved 2009-01-02.
^ Esiri, Margaret M.; Booss, John (2003). Viral Encephalitis in Humans. Washington, D.C: ASM Press. pp. 117. ISBN 1-55581-240-6.
^ Binns, Matthew M.; Smith, Geoffrey L.; Andrew, Marion E.; Artois, Marc; Aubert, Michel; Blancou, Jean; Boursnell, Michael E. G.; Boyle, David B.; Brochier, Bernard; et al. (1992). Recombinant Poxviruses. Boca Raton, Florida, United States: CRC Press. pp. 1–343. ISBN 0-8493-6179-6.

v t e Blood tests for infectious disease
Bacterial infection	syphilis Venereal Disease Research Laboratory test rapid plasma reagin Wassermann test Fluorescent treponemal antibody absorption test Abelin reaction Rickettsia Weil–Felix test Helicobacter HelicoCARE direct Streptococcus Anti-streptolysin O
Viral infection	HIV testing Branched DNA assay mChip Epstein–Barr virus Heterophile antibody test Dengue fever NS1 antigen test measles Warthin–Finkeldey cell Inclusion bodies Downie bodies B type inclusion Orthopoxvirus inclusion bodies rabies Negri bodies Cowdry bodies yellow fever Councilman body Tzanck test
Protozoan infection	toxoplasmosis Sabin–Feldman dye test malaria Diagnosis of malaria Schüffner's dots
Bloodstream infections	Blood culture Viremia Fungemia Parasitemia Algaemia
General	C-reactive protein Procalcitonin

References

Further reading