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Protein-coding gene in humans
B-cell CLL/lymphoma 7 protein family member A is a protein that in humans is encoded by the BCL7A gene located in the chromosome 12 (Cytogenetic band: 12q24.31).[ 5]
This gene codifies for a protein that belongs to the SWI/SNF chromatin remodelling complex, a complex that is able to modify the interations between DNA and histones using the energy of the ATP hydrolysis . It has found recurrently mutated in lymphomas [ 6] promoter hypermetylation in haematological malignancies .[ 7] [ 8]
^ a b c ENSG00000110987 GRCh38: Ensembl release 89: ENSG00000282873, ENSG00000110987 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029438 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^
"BCL7A BAF chromatin remodeling complex subunit BCL7A [ Homo sapiens (human) ]" . Retrieved 2019-04-28 .
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This article incorporates text from the United States National Library of Medicine , which is in the public domain .
