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Anjelica Gonzalez

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Anjelica Gonzalez
Alma mater
Known forPremieBreathe
Scientific career
FieldsDevelopment of biomimetic materials for use in investigation of immunology, inflammation and fibrosis
InstitutionsYale University
Doctoral advisor

Anjelica L. Gonzalez is a biomedical engineer, scientist, Associate Professor of Biomedical Engineering[1] at Yale University, and is part of the Vascular Biology and Therapeutics Program.[2] Her work focuses primarily on biomimetic materials, or the development of materials that mimic human organs, to study how drugs and other medical interventions can reverse tissue damage caused by environmental pollutants, inflammation, and diseases. She is also the principal investigator for the "PremieBreathe" device which has developed a low-cost device designed to save the lives of premature babies in settings that lack safe respiratory devices.

Early life

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Gonzalez's cultural background is Mexican-American and African-American.[3] She grew up Las Vegas, Nevada, and in the Moapa Valley in Nevada. She was raised along with her brother by a single mother who is a blackjack dealer.[4] Her grandfather was director of the Moapa Valley irrigation system and was an early inspiration for her scientific career. She has also discussed being scientifically influenced by her father, a diesel mechanic, who instilled the principles of engineering, and by her mother's mathematical skills.[5]

Education

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Gonzalez attended high school in Las Vegas, and went on to attend Utah State University[2] in Logan, Utah. In 1999, Anjelica received her Bachelor of Science in Biological Engineering.[6] She initially planned to pursue a career in computational irrigation management, but later began taking biology courses that eventually influenced her change of career course. Also influencing this decision was a Baylor University summer program where she worked with pulmonary specialist Dr. Aladin Boriek. Gonzalez describes this experience as "the first realization that I had that the math, computational skills, the understanding of mechanics and physics, could translate to the physiological system, to human biology."[3] During her time at Baylor, she worked under Larry McIntire, who she found to be very influential for his work in engineering.[7]

Upon graduating, Gonzalez became the first person from her family to receive a bachelor's degree. In 2004, she obtained her Doctor of Philosophy in Computational Biology[6][8] from Baylor College of Medicine[2] in Houston, Texas.

During her time at Baylor College of Medicine, Gonzalez was only one of a few minority students in her program, and the only woman actively participating as a graduate student.[9]

Career

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After graduating from Baylor, Gonzalez conducted post-doctoral work in the Leukocyte Biology and Pediatric Intensive Care Unit at Texas Children's Hospital. She joined the Yale faculty as an associate research scientist in 2007.[10] After two years in this role, she joined the Yale biomedical engineering faculty and in 2014 was appointed the Donna L. Dubinsky Assistant Professor of Biomedical Engineering.[11] As of 2022 she is an appointed associate professor in the Department of Biomedical Engineering at Yale University.[12]

At Yale, Gonzalez developed PremieBreathe, a low-cost mobile neonatal respiratory device meant to treat the breathing problems of prematurely born babies. PremieBreathe was developed and studied in Ethiopia and is supported by the US Agency for International Development (USAID), the Bill and Melinda Gates Foundation, and NCIIA/Venturewell.[13][14][15] She is also a founder of Aero Therapeutics, which produces the device.[16]

In 2020, she was also appointed faculty director of the Tsai Center for Innovative Thinking at Yale University (Tsai CITY).[17] In 2022, Gonzalez was appointed head of Davenport College, making her the first Black woman to serve as head of college in Yale's history.[18]

Her areas of research include:[19]

Personal life

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Gonzalez has twin sons and resides in New Haven, Connecticut. She plays the violin and enjoys sewing her own clothing.[10]

Awards & honors

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Anjelica has earned numerous awards and distinctions. Here are a selection:

Publications

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Books

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  • Engineering Biomaterials for Regenerative Medicine: Novel Technologies for Clinical Applications, Chp. 6, p. 143-160 (co-author) Springer (2011)[28]

Journals

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Gonzalez has more than 60 publications. Her most cited work has been cited over 120 times.

Here is a selection of her works that have been cited over 70 times each:[19]

  • Nanowire substrate-based laser scanning cytometry for quantitation of circulating tumor cells (2012)

SK Lee, GS Kim, Y Wu, DJ Kim, Y Lu, M Kwak, L Han, JH Hyung, JK Seol, ... Nano Letters

  • Extracellular mitochondrial DNA is generated by fibroblasts and predicts death in idiopathic pulmonary fibrosis (2017)

C Ryu, H Sun, M Gulati, JD Herazo-Maya, Y Chen, A Osafo-Addo, ... American Journal of Respiratory and Critical Care Medicine

  • Daily egg consumption in hyperlipidemic adults-Effects on endothelial function and cardiovascular risk (2010)

V Njike, Z Faridi, S Dutta, AL Gonzalez-Simon, DL Katz Nutrition Journal

  • Integrin interactions with immobilized peptides in polyethylene glycol diacrylate hydrogels (2004)

AL Gonzalez, AS Gobin, JL West, LV McIntire, CW Smith Tissue engineering

Articles

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Gonzalez has contributed opinion articles to multiple publications, including:

Quotes

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Gonzalez speaks out for women and minorities:[29]

  • "Data shows that women and minorities are selectively sorted out of engineering, math and science careers."
  • "Additionally, when they do speak up and exhibit their skills, young women are often overlooked or blatantly dismissed."
  • "Studies have evaluated whether hard work is rewarded in a fair manner, and determined that cultural norms and implicit biases in many cases prevent equal reward for equal efforts."

References

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  1. ^ "New insight to the brain's response to injury". medicalxpress.com. Retrieved 26 March 2021.
  2. ^ a b c d e f "Faculty & Research: Anjelica Gonzalez". seas.yale.edu. Retrieved 24 March 2021.
  3. ^ a b Physics, American Institute of (2022-02-14). "Anjelica Gonzalez". www.aip.org. Retrieved 2022-04-28.
  4. ^ Gonzalez, Anjelica L. (2013-05-11). "A Life of Science Was in the Cards". The New York Times. ISSN 0362-4331. Retrieved 2022-04-28.
  5. ^ Gonzalez, Anjelica L. (2017-02-25). "Her Scientific Discovery: Support". The New York Times. ISSN 0362-4331. Retrieved 2022-04-28.
  6. ^ a b "Yale University: Anjelica Gonzalez". gonzalezlab.yale.edu. Retrieved 24 March 2021.
  7. ^ Gonzalez, Anjelica (21 October 2020). "Oral Histories: Anjelica Gonzalez" (Interview). Interviewed by David Zierler. Video conference: American Institute of Physics. Archived from the original on 7 October 2022.
  8. ^ "Anjelica Gonzalez". www.sciencemag.org. Retrieved 24 March 2021.
  9. ^ "Transitioning From Undergraduate to Graduate School". www.science.org. Retrieved 2022-04-28.
  10. ^ a b c "Welcome | Davenport College". davenport.yalecollege.yale.edu. Retrieved 2022-04-28.
  11. ^ "Anjelica Gonzalez appointed Dubinsky Assistant Professor of Biomedical Engineering". YaleNews. 2014-12-15. Retrieved 2022-04-28.
  12. ^ a b "Engineering Human Microvasculature in Inflammatory and Fibrotic Disease". www.bme.ufl.edu. Retrieved 24 March 2021.
  13. ^ "Yale School of Engineering & Applied Science: Anjelica Gonzalez Takes Award in Saving Lives at Birth Competition". seas.yale.edu. Retrieved 24 March 2021.
  14. ^ "Yale News: PremieBreathe gives premature babies a better chance". news.yale.edu. Retrieved 24 March 2021.
  15. ^ Yang, Cindy. "PremieBreathe: A Cost-Effective, Life-Saving Respiratory Device". Yale Scientific: The Nation's Oldest College Science Publication. Retrieved 24 March 2021.
  16. ^ "The Team". AeroTx. Retrieved 2022-04-28.
  17. ^ "Anjelica Gonzalez Named Tsai CITY Faculty Director". Tsai CITY. Retrieved 2022-04-28.
  18. ^ Cook, Sarah; Porayouw, William (2022-04-22). "Anjelica Gonzalez and Paul North named Davenport and JE heads of college". Yale Daily News. Retrieved 2022-04-26.
  19. ^ a b "Anjelica L Gonzalez: Donna L. Dubinsky Associate Professor of Biomedical Engineering, Yale University". Google Scholar. Retrieved 24 March 2021.
  20. ^ "Tsai Center for Innovative Thinking: Anjelica Gonzalez". city.yale.edu. Retrieved 24 March 2021.
  21. ^ anonymous. "Gonzalez Inducted Into Bouchet Honor Society". Yale School of Engineering & Applied Science. Retrieved 2022-04-28.
  22. ^ "Discussions on Science and Diversity". seas.yale.edu. Retrieved 24 March 2021.
  23. ^ "Yale launches diversity in science video series with Anjelica Gonzalez and Manu Platt". Biomedical Engineering Society. Retrieved 24 March 2021.
  24. ^ "STEM and Social Inclusion Series starts with speaker Anjelica Gonzalez". yaledailynews.com. Retrieved 24 March 2021.
  25. ^ "Yale named Top Ten Center of Biomedical Research by The Hartwell Foundation". yale.edu. Retrieved 26 March 2021.
  26. ^ "Anjelica Gonzalez honored with 2018 BMES Diversity Award". news.yale.edu. Retrieved 26 March 2021.
  27. ^ "Diversity and Inclusion". www.bmes.org. Retrieved 26 March 2021.
  28. ^ Bhatia, Sujata K. (10 November 2011). Chapter 6: Host Response to Biomaterials. Springer. ISBN 978-1-4614-1080-5. Retrieved 26 March 2021.
  29. ^ "Her Scientific Discovery: Support". The New York Times. Retrieved 24 March 2021.
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