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Amanda Paulovich

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Amanda Paulovich
Alma materCarnegie Mellon University
University of Washington
AwardsHUPO Distinguished Achievement in Proteomic Sciences Award (2015)
Scientific career
FieldsBiology
InstitutionsFred Hutchinson Cancer Research Center
Thesis The Regulation of S Phase Progression Rate in Yeast in Response to DNA Damage  (1996)
Doctoral advisorLeland H. Hartwell

Amanda Grace Paulovich is an oncologist, and a pioneer in proteomics using multiple reaction monitoring mass spectrometry to study tailored cancer treatment.

Education

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Paulovich received a BS in Biological Sciences from Carnegie Mellon University in 1988,[1] a PhD in Genetics from University of Washington in 1996, under the direction of Leland Hartwell.[2] She also received a MD from University of Washington in 1998.[3] Follow her residency in Internal Medicine at Massachusetts General Hospital, she also completed a Postdoctoral Fellowship in Computational Biology at the Massachusetts Institute of Technology Whitehead Center for Genomic Research in 2003, and a Fellowship in Medical Oncology at the Dana Farber Cancer Institute in 2004.[1][4]

Career

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Paulovich is a Professor in Clinical Research, an Aven Foundation Endowed Chair, and the Director of Early Detection Initiative at the Fred Hutchinson Cancer Research Center.[5][6] She was inducted to the American Society for Clinical Inviestigation in 2012.[7]

Paulovich is an expert in proteomics.[8] Her targeted proteomics method uses multiple reaction monitoring mass spectrometry to target cancer biomarkers with ongoing clinical trials,[9] and was named Method of the Year in 2012 by Nature Methods.[10][11] She founded Precision Assays in 2016,[12] whose rights to targeted assays were acquired by CellCarta in 2022.[13][14]

Awards

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Patent applications

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  • Identification and use of biomarkers for detection and quantification of the level of radiation exposure in a biological sample (2011) US 20130052668 A1[19]
  • Compositions and methods for reliably detecting and/or measuring the amount of a modified target protein in a sample (2011) US 20130052669 A1[20]

References

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  1. ^ a b "Amanda Paulovich, M.D., Ph.D." Fred Hutch. Retrieved 2022-06-06.
  2. ^ "UW Genome Sciences: Alumni". www.gs.washington.edu. Retrieved 2022-06-06.
  3. ^ "Alumni Directory | Medical Scientist Training Program". Retrieved 2022-06-06.
  4. ^ "Doctors Dr. Amanda G. Paulovich MD". U.S. News & World Report. Retrieved June 6, 2022.
  5. ^ "MCS Alumna Develops New Technologies for Early Cancer Detection". Carnegie Mellon University Carnegie Mellon Today Archives. September 1, 2004. Retrieved June 6, 2022.
  6. ^ Pittsburgh, A. Carnegie Mellon University Publication 5000 Forbes Avenue; Pa 15213268-2000. "MCS Alumna Develops New Technologies for Early Cancer Detection". Carnegie Mellon Today. Retrieved 2022-06-06.{{cite web}}: CS1 maint: numeric names: authors list (link)
  7. ^ "The American Society for Clinical Investigation". Archived from the original on 2022-10-18. Retrieved 2022-06-08.
  8. ^ "Interviewer List | Biocompare: The Buyer's Guide for Life Scientists". www.biocompare.com. Retrieved 2022-06-08.
  9. ^ "CPTAC Contributes to the Identification of a Novel Pharmacodynamic Biomarker for Clinical Trial Use | Office of Cancer Clinical Proteomics Research". proteomics.cancer.gov. Retrieved 2022-06-08.
  10. ^ "Beyond genomics: Using proteomics to target tumors". ScienceDaily. Retrieved 2022-06-08.
  11. ^ "Fred Hutch's Paulovich lab to lead protein assay work for Beau Biden Cancer Moonshot". American Association for the Advancement of Science (AAAS) EurekAlert! Archive. 2017-02-06. Retrieved 2022-06-08.
  12. ^ "PRECISION ASSAYS, LLC :: Washington (US) :: OpenCorporates". opencorporates.com. Retrieved 2022-06-08.
  13. ^ "CellCarta Acquires Next-Generation Immuno-MRM Assays from Precision Assays". CellCarta. Retrieved 2022-06-08.
  14. ^ CellCarta. "CellCarta expands it proteomics portfolio with the acquisition of next-generation immuno-MRM assays from Precision Assays". www.newswire.ca. Retrieved 2022-06-08.
  15. ^ "Pappu recognized as 'woman to watch' in life science". WSU Insider. Retrieved 2022-06-06.
  16. ^ "MSACL-Paulovich". www.msacl.org. Retrieved 2022-06-06.
  17. ^ "HUPO - Past Award Recipients". www.hupo.org. Retrieved 2022-06-06.
  18. ^ "SCIEX Partners with the Paulovich Lab at Fred Hutchinson Cancer Research Center to Advance Cancer Research Reproducibility". www.businesswire.com. 2015-09-22. Retrieved 2022-06-06.
  19. ^ US application 20130052668A1  Amanda G. Paulovich, Richard G. Ivey/Fred Hutchinson Cancer Research Center: "Identification and use of biomarkers for detection and quantification of the level of radiation exposure in a biological sample" filing date 29.04.2011
  20. ^ US application 20130052669A1  Amanda G. Paulovich, Richard G. Ivey/Fred Hutchinson Cancer Research Center: "Compositions and methods for reliably detecting and/or measuring the amount of a modified target protein in a sample" filing date 29.04.2011
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